5,6-DIHYDROXY-2-THIOPHEN-2-YL-PYRIMIDINE-4-CARBOXYLIC ACID

Base Information

Chemical Name:5,6-DIHYDROXY-2-THIOPHEN-2-YL-PYRIMIDINE-4-CARBOXYLIC ACID
CAS No.:391680-79-8
Molecular Formula:C9H6N2O4S
Molecular Weight:238.22000
Hs Code.:
Mol file:391680-79-8.mol

Synonyms:5,6-Dihydroxy-2-thiophen-2-yl-pyrimidine-4-carboxylic acid;2-(2-Thienyl)-4,5-dihydroxypyrimidine-6-carboxylate;4-Pyrimidinecarboxylic acid,5,6-dihydroxy-2-(2-thienyl);6-(dihydroxymethylidene)-2-thiophen-2-yl-1H-pyrimidine-4,5-dione;

Suppliers and Price of 5,6-DIHYDROXY-2-THIOPHEN-2-YL-PYRIMIDINE-4-CARBOXYLIC ACID

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

J&W Pharmlab
5,6-Dihydroxy-2-thiophen-2-yl-pyrimidine-4-carboxylicacid 97%
500mg
$ 740.00

American Custom Chemicals Corporation
5,6-DIHYDROXY-2-THIOPHEN-2-YL-PYRIMIDINE-4-CARBOXYLIC ACID 96.00%
5MG
$ 499.50

Total 3 raw suppliers

Chemical Property of 5,6-DIHYDROXY-2-THIOPHEN-2-YL-PYRIMIDINE-4-CARBOXYLIC ACID

Chemical Property:

PSA：131.52000
LogP:0.90220

Purity/Quality:

97% ^*data from raw suppliers

5,6-Dihydroxy-2-thiophen-2-yl-pyrimidine-4-carboxylicacid 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 5,6-DIHYDROXY-2-THIOPHEN-2-YL-PYRIMIDINE-4-CARBOXYLIC ACID

There total 6 articles about 5,6-DIHYDROXY-2-THIOPHEN-2-YL-PYRIMIDINE-4-CARBOXYLIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 391680-92-5
methyl 5,6-dihydroxy-2-thien-2-ylpyrimidine-4-carboxylate

: 391680-79-8
5,6-dihydroxy-2-(thiophen-2-yl)pyrimidine-4-carboxylic acid

Guidance literature:: With lithium hydroxide; In tetrahydrofuran;
DOI:10.1016/j.bmcl.2004.07.075

Reference yield:

: 53370-51-7
N'-hydroxythiophene-2-carboximidamide

: 391680-79-8
5,6-dihydroxy-2-(thiophen-2-yl)pyrimidine-4-carboxylic acid

Guidance literature:: Multi-step reaction with 3 steps

1: Et₃N / CH₂Cl₂ / 3 h / Heating

2: xylene / 140 °C

3: aq. NaOH / methanol / 0.25 h / 80 °C

With sodium hydroxide; triethylamine; In methanol; dichloromethane; xylene;
DOI:10.1021/jm051064t

Reference yield:

: 878650-00-1
(E)-2-[(Thiophene-2-carboximidoyl)-aminooxy]-but-2-enedioic acid dimethyl ester

: 391680-79-8
5,6-dihydroxy-2-(thiophen-2-yl)pyrimidine-4-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: xylene / 140 °C

2: aq. NaOH / methanol / 0.25 h / 80 °C

With sodium hydroxide; In methanol; xylene;
DOI:10.1021/jm051064t