5-(4-Fluorobenzyl)-1,3,4-thiadiazol-2-amine

Base Information

Chemical Name:5-(4-Fluorobenzyl)-1,3,4-thiadiazol-2-amine
CAS No.:39181-55-0
Molecular Formula:C9H8FN3S
Molecular Weight:209.247
Hs Code.:2934100090
European Community (EC) Number:866-989-3
DSSTox Substance ID:DTXSID50353437
Wikidata:Q82131036
ChEMBL ID:CHEMBL1718411
Mol file:39181-55-0.mol

Synonyms:5-(4-fluorobenzyl)-1,3,4-thiadiazol-2-amine;39181-55-0;5-[(4-fluorophenyl)methyl]-1,3,4-thiadiazol-2-amine;2-AMINO-5-(4-FLUOROBENZYL)-1,3,4-THIADIAZOLE;5-(4-Fluoro-benzyl)-[1,3,4]thiadiazol-2-ylamine;CBMicro_033228;Cambridge id 5790269;Oprea1_285437;Oprea1_386963;MLS000768909;SCHEMBL602492;CHEMBL1718411;DTXSID50353437;HMS2783N23;MFCD01364163;STK384983;AKOS000625441;LS-04227;SMR000433652;BIM-0033243.P001;CS-0217223;EN300-71464;AB00097008-01;5-(4-fluorobenzyl)-1,3,4-thiadiazol-2-ylamine;AM-900/25025016;SR-01000418419;SR-01000418419-1;F0452-1736;Z445126236

Suppliers and Price of 5-(4-Fluorobenzyl)-1,3,4-thiadiazol-2-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5-(4-Fluorobenzyl)-1,3,4-thiadiazol-2-amine
100mg
$ 90.00

SynQuest Laboratories
5-(4-Fluorobenzyl)-1,3,4-thiadiazol-2-amine
1 g
$ 263.00

Matrix Scientific
2-Amino-5-(4-fluorobenzyl)-1,3,4-thiadiazole
1g
$ 378.00

Crysdot
5-(4-Fluorobenzyl)-1,3,4-thiadiazol-2-amine 95+%
1g
$ 429.00

Apolloscientific
5-(4-Fluorobenzyl)-1,3,4-thiadiazol-2-amine
1g
$ 164.00

American Custom Chemicals Corporation
2-AMINO-5-(4-FLUOROBENZYL)-1,3,4-THIADIAZOLE 95.00%
5G
$ 1421.65

American Custom Chemicals Corporation
2-AMINO-5-(4-FLUOROBENZYL)-1,3,4-THIADIAZOLE 95.00%
2.5G
$ 1147.43

American Custom Chemicals Corporation
2-AMINO-5-(4-FLUOROBENZYL)-1,3,4-THIADIAZOLE 95.00%
1G
$ 808.89

Alichem
5-(4-Fluorobenzyl)-1,3,4-thiadiazol-2-amine
1g
$ 367.50

AK Scientific
5-(4-Fluorobenzyl)-1,3,4-thiadiazol-2-amine
5g
$ 1164.00

Total 7 raw suppliers

Chemical Property of 5-(4-Fluorobenzyl)-1,3,4-thiadiazol-2-amine

Chemical Property:

PSA：80.04000
LogP:2.43140
XLogP3:2.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:209.04229660
Heavy Atom Count:14
Complexity:185

Purity/Quality:

98%min ^*data from raw suppliers

5-(4-Fluorobenzyl)-1,3,4-thiadiazol-2-amine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi,Xn
Statements: 22

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1CC2=NN=C(S2)N)F

Technology Process of 5-(4-Fluorobenzyl)-1,3,4-thiadiazol-2-amine

There total 4 articles about 5-(4-Fluorobenzyl)-1,3,4-thiadiazol-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 79-19-6
thiosemicarbazide

: 405-50-5
p-Fluorophenylacetic acid

: 39181-55-0
2-amino-5-(4-fluorobenzyl)-1,3,4-thiadiazole

Guidance literature:: With trichlorophosphate; for 0.75h; Reflux;
DOI:10.1007/s00044-011-9659-4

Reference yield: 52.0%

: 39181-55-0
2-amino-5-(4-fluorobenzyl)-1,3,4-thiadiazole

Guidance literature:: With trichlorophosphate; for 0.75h; Reflux;

Reference yield:

: 39203-09-3
2-[(4-fluorophenyl)acetyl]hydrazinecarbothioamide

: 39181-55-0
2-amino-5-(4-fluorobenzyl)-1,3,4-thiadiazole

Guidance literature:: 2-[(4-fluorophenyl)acetyl]hydrazinecarbothioamide; With sulfuric acid; at -10 - 0 ℃; for 3h;

With sodium hydroxide; In water; at -10 - 0 ℃;