2-(4-Chlorophenyl)-α-methyl-7-benzoxazoleacetic acid

Base Information

Chemical Name:2-(4-Chlorophenyl)-α-methyl-7-benzoxazoleacetic acid
CAS No.:58902-62-8
Molecular Formula:C₁₆H₁₂ClNO₃
Molecular Weight:301.729
Hs Code.:
Mol file:58902-62-8.mol

Synonyms:2-[2-(4-chloro-phenyl)-benzooxazol-7-yl]-propionic acid;

Suppliers and Price of 2-(4-Chlorophenyl)-α-methyl-7-benzoxazoleacetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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Total 4 raw suppliers

Chemical Property of 2-(4-Chlorophenyl)-α-methyl-7-benzoxazoleacetic acid

Chemical Property:

Vapor Pressure:9.61E-09mmHg at 25°C
Melting Point:198-199 °C(Solv: methanol (67-56-1))
Boiling Point:446.2°C at 760 mmHg
PKA:4.30±0.30(Predicted)
Flash Point:223.6°C
PSA：63.33000
Density:1.362g/cm³
LogP:4.33630

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

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Technology Process of 2-(4-Chlorophenyl)-α-methyl-7-benzoxazoleacetic acid

There total 4 articles about 2-(4-Chlorophenyl)-α-methyl-7-benzoxazoleacetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 88-75-5,78813-12-4
2-hydroxynitrobenzene

: 58902-62-8
2-[2-(4-chloro-phenyl)-benzooxazol-7-yl]-propionic acid

Guidance literature:: Multi-step reaction with 4 steps

1: NaOEt, KI / ethanol

2: 170 - 200 °C

3: Zn, aq. NH₄Cl / ethanol

4: (i) Py, (ii) KIO₄, aq. KMnO₄, acetone

With sodium ethanolate; ammonium chloride; potassium iodide; zinc; In ethanol;
DOI:10.1021/jm00211a039

Reference yield:

: 31225-05-5
2-(1-methyl-2-propen-1-yl)-6-nitrophenol

: 58902-62-8
2-[2-(4-chloro-phenyl)-benzooxazol-7-yl]-propionic acid

Guidance literature:: Multi-step reaction with 2 steps

1: Zn, aq. NH₄Cl / ethanol

2: (i) Py, (ii) KIO₄, aq. KMnO₄, acetone

With ammonium chloride; zinc; In ethanol;
DOI:10.1021/jm00211a039

Reference yield:

: 30065-88-4
3-methylallyl 2-nitrophenyl ether

: 58902-62-8
2-[2-(4-chloro-phenyl)-benzooxazol-7-yl]-propionic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 170 - 200 °C

2: Zn, aq. NH₄Cl / ethanol

3: (i) Py, (ii) KIO₄, aq. KMnO₄, acetone

With ammonium chloride; zinc; In ethanol;
DOI:10.1021/jm00211a039