1-(4-Fluorophenyl)-3-[4-(2-methoxyphenyl)piperazin-1-yl]pyrrolidine-2,5-dione

Base Information

Chemical Name:1-(4-Fluorophenyl)-3-[4-(2-methoxyphenyl)piperazin-1-yl]pyrrolidine-2,5-dione
CAS No.:5304-98-3
Molecular Formula:C21H22FN3O3
Molecular Weight:383.4161
Hs Code.:
DSSTox Substance ID:DTXSID80385620
ChEMBL ID:CHEMBL1329533

Synonyms:1-(4-fluorophenyl)-3-[4-(2-methoxyphenyl)piperazin-1-yl]pyrrolidine-2,5-dione;5304-98-3;CBMicro_016474;MLS001211468;CHEMBL1329533;DTXSID80385620;HMS2836H08;CCG-5574;STK029476;AKOS000583651;AKOS022084030;SMR000514018;BIM-0016593.P001;SR-01000428708;SR-01000428708-1;1-(4-Fluoro-phenyl)-3-[4-(2-methoxy-phenyl)-piperazin-1-yl]-pyrrolidine-2,5-dione

Suppliers and Price of 1-(4-Fluorophenyl)-3-[4-(2-methoxyphenyl)piperazin-1-yl]pyrrolidine-2,5-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-(4-Fluorophenyl)-3-[4-(2-methoxyphenyl)piperazin-1-yl]pyrrolidine-2,5-dione

Chemical Property:

Vapor Pressure:7.32E-15mmHg at 25°C
Boiling Point:610.9°C at 760 mmHg
Flash Point:323.2°C
Density:1.314g/cm³
XLogP3:2.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:4
Exact Mass:383.16451973
Heavy Atom Count:28
Complexity:573

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=CC=C1N2CCN(CC2)C3CC(=O)N(C3=O)C4=CC=C(C=C4)F

Technology Process of 1-(4-Fluorophenyl)-3-[4-(2-methoxyphenyl)piperazin-1-yl]pyrrolidine-2,5-dione

There total 3 articles about 1-(4-Fluorophenyl)-3-[4-(2-methoxyphenyl)piperazin-1-yl]pyrrolidine-2,5-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 4354-67-0
2-cyclohexylmalonic acid

: 5304-98-3
2,4-Dicyclohexyl-isoxazolidin-3,5-dion

Guidance literature:: Multi-step reaction with 2 steps

1: SOCl₂

2: (i) (alkaline hydrolysis), (ii) SOCl₂, (iii) /BRN= 605426/, Py, CHCl₃

With thionyl chloride;
DOI:10.1002/hlca.19650480817