4-(2-Chloroquinazolin-4-yl)morpholine

Base Information

Chemical Name:4-(2-Chloroquinazolin-4-yl)morpholine
CAS No.:39213-05-3
Molecular Formula:C12H12ClN3O
Molecular Weight:249.7
Hs Code.:2934999090
DSSTox Substance ID:DTXSID30368165
Wikidata:Q82154522
Mol file:39213-05-3.mol

Synonyms:4-(2-chloroquinazolin-4-yl)morpholine;39213-05-3;2-chloro-4-(morpholin-4-yl)quinazoline;2-chloro-4-morpholinoquinazoline;MFCD03083869;2-chloro-4-morpholino-quinazoline;SCHEMBL4095134;DTXSID30368165;NJBDGZVAZRMIFM-UHFFFAOYSA-N;STL582150;2-Chloro-4-morpholin-4-ylquinazoline;AKOS001283002;2-chloro-4-(4-morpholinyl)Quinazoline;2-Chloro-4-morpholin-4-yl-quinazoline;CCG-290905;FT-0718721;F81645;JXX

Suppliers and Price of 4-(2-Chloroquinazolin-4-yl)morpholine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
2-Chloro-4-morpholinoquinazoline
10g
$ 2300.00

Matrix Scientific
2-Chloro-4-morpholinoquinazoline
5g
$ 1355.00

Matrix Scientific
2-Chloro-4-morpholinoquinazoline
1g
$ 490.00

Crysdot
4-(2-Chloroquinazolin-4-yl)morpholine 95+%
1g
$ 392.00

Chemenu
4-(2-chloroquinazolin-4-yl)morpholine 95%
1g
$ 371.00

American Custom Chemicals Corporation
2-CHLORO-4-MORPHOLINOQUINAZOLINE 95.00%
5MG
$ 459.42

Alfa Aesar
2-Chloro-4-(4-morpholinyl)quinazoline, 97%
1g
$ 242.00

Alfa Aesar
2-Chloro-4-(4-morpholinyl)quinazoline, 97%
250mg
$ 75.80

AK Scientific
4-(2-Chloroquinazolin-4-yl)morpholine
10g
$ 3155.00

AK Scientific
4-(2-Chloroquinazolin-4-yl)morpholine
5g
$ 1879.00

Total 7 raw suppliers

Chemical Property of 4-(2-Chloroquinazolin-4-yl)morpholine

Chemical Property:

Boiling Point:391.3±42.0 °C(Predicted)
PKA:4.10±0.30(Predicted)
PSA：38.25000
Density:1.347±0.06 g/cm3(Predicted)
LogP:2.18480
Storage Temp.:2-8°C
XLogP3:2.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:249.0668897
Heavy Atom Count:17
Complexity:260

Purity/Quality:

99% ^*data from raw suppliers

2-Chloro-4-morpholinoquinazoline ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1COCCN1C2=NC(=NC3=CC=CC=C32)Cl

Technology Process of 4-(2-Chloroquinazolin-4-yl)morpholine

There total 3 articles about 4-(2-Chloroquinazolin-4-yl)morpholine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 110-91-8,99108-56-2
morpholine

: 607-68-1
2,4-dichloroquinazoline

: 39213-05-3
2-chloro-4-morpholino-quinazoline

Guidance literature:: In acetonitrile; for 5h; regioselective reaction; Reflux;
DOI:10.1039/c6ra21219k

Reference yield:

: 86-96-4
1,2,3,4-tetrahydro-quinazoline-2,4-dione

: 39213-05-3
2-chloro-4-morpholino-quinazoline

Guidance literature:: Multi-step reaction with 2 steps

1: sodium hydrogencarbonate; trichlorophosphate / hexane; N,N-dimethyl-aniline; benzene

2: ethanol; water

With sodium hydrogencarbonate; trichlorophosphate; In ethanol; hexane; water; N,N-dimethyl-aniline; benzene;