N-[4-Amino-3-(trifluoromethyl)phenyl]-2-methylpropanamide

Base Information

Chemical Name:N-[4-Amino-3-(trifluoromethyl)phenyl]-2-methylpropanamide
CAS No.:39235-51-3
Molecular Formula:C11H13F3N2O
Molecular Weight:246.232
Hs Code.:2924299090
DSSTox Substance ID:DTXSID30588326
Nikkaji Number:J2.820.821I
Wikidata:Q82480933
Mol file:39235-51-3.mol

Synonyms:39235-51-3;N-[4-AMINO-3-(TRIFLUOROMETHYL)PHENYL]-2-METHYLPROPANAMIDE;N-[4-Amino-3-(trifluoromethyl)phenyl]-2-methylpropanamide (FLU-6);SCHEMBL11511196;DTXSID30588326;AKOS000133020;MCULE-7448041713;4'-amino-3'-trifluoromethylisobutyranilide;2-methyl-N-[4-amino-3-(trifluoromethyl)phenyl]propanamide

Suppliers and Price of N-[4-Amino-3-(trifluoromethyl)phenyl]-2-methylpropanamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N-[4-Amino-3-(trifluoromethyl)phenyl]-2-methylpropanamide(FLU-6)
25mg
$ 1230.00

Biosynth Carbosynth
N-[4-Amino-3-(trifluoromethyl)phenyl]-2-methylpropanamide
2 mg
$ 254.40

Biosynth Carbosynth
N-[4-Amino-3-(trifluoromethyl)phenyl]-2-methylpropanamide
1 mg
$ 139.90

Biosynth Carbosynth
N-[4-Amino-3-(trifluoromethyl)phenyl]-2-methylpropanamide
5 mg
$ 462.50

Biosynth Carbosynth
N-[4-Amino-3-(trifluoromethyl)phenyl]-2-methylpropanamide
10 mg
$ 840.90

Biosynth Carbosynth
N-[4-Amino-3-(trifluoromethyl)phenyl]-2-methylpropanamide
25 mg
$ 1529.00

American Custom Chemicals Corporation
N-[4-AMINO-3-(TRIFLUOROMETHYL)PHENYL]-2-METHYLPROPANAMIDE 95.00%
5MG
$ 497.02

AK Scientific
N-[4-Amino-3-(trifluoromethyl)phenyl]-2-methylpropanamide
5mg
$ 674.00

AK Scientific
N-[4-Amino-3-(trifluoromethyl)phenyl]-2-methylpropanamide
2mg
$ 393.00

Total 7 raw suppliers

Chemical Property of N-[4-Amino-3-(trifluoromethyl)phenyl]-2-methylpropanamide

Chemical Property:

Vapor Pressure:0.002mmHg at 25°C
Refractive Index:1.527
Boiling Point:289.154 °C at 760 mmHg
PKA:13.96±0.70(Predicted)
Flash Point:128.676 °C
PSA：58.61000
Density:1.284 g/cm³
LogP:4.11280
XLogP3:2.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:246.09799753
Heavy Atom Count:17
Complexity:278

Purity/Quality:

98%Min ^*data from raw suppliers

N-[4-Amino-3-(trifluoromethyl)phenyl]-2-methylpropanamide(FLU-6) ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)C(=O)NC1=CC(=C(C=C1)N)C(F)(F)F
Uses A metabolite of Flutamide (FLU-6 or M9). A metabolite of Flutamide (F598850) (FLU-6 or M9).

Technology Process of N-[4-Amino-3-(trifluoromethyl)phenyl]-2-methylpropanamide

There total 6 articles about N-[4-Amino-3-(trifluoromethyl)phenyl]-2-methylpropanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 13311-84-7
Flutamide

: 39235-51-3
2-methyl-N-[4-amino-3-(trifluoromethyl)phenyl]propanamide

Guidance literature:: With borane-ammonia complex; jacquesdietrichite; In d⁽⁴⁾-methanol; water-d2; at 20 ℃; for 1h;
DOI:10.1002/cctc.202000150

Reference yield: 51.0%

: N-(4-nitrophenyl)isobutyramide

: 75-63-8
Bromotrifluoromethane

: 39235-51-3
2-methyl-N-[4-amino-3-(trifluoromethyl)phenyl]propanamide

Guidance literature:: With 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; palladium diacetate; caesium carbonate; catacxium A; In acetone; at 130 ℃; for 40h; regioselective reaction; Inert atmosphere; Autoclave;
DOI:10.1002/anie.201511131

Reference yield: 11.1%

: 13311-84-7
Flutamide

: 393-11-3
4-nitro-3-(trifluoromethyl)benzeneamine

: 1579-89-1
N-[4-amino-3-(trifluoromethyl)phenyl]acetamide

: 39235-51-3
2-methyl-N-[4-amino-3-(trifluoromethyl)phenyl]propanamide

Guidance literature:: With Rhodotorula mucilaginosa (ATCC 20129); In N,N-dimethyl-formamide; at 20 ℃; for 336h; Physiological pH; Microbiological reaction;
DOI:10.1248/cpb.58.562