2,6-Di(1H-imidazol-1-yl)pyridine

Base Information

• Chemical Name: 2,6-Di(1H-imidazol-1-yl)pyridine
• CAS No.: 39242-17-6
• Molecular Formula: C11H9N5
• Molecular Weight: 211.226
• Hs Code.: 2933990090
• DSSTox Substance ID: DTXSID00477758
• Nikkaji Number: J1.735.178H
• Wikidata: Q82310654
• Mol file: 39242-17-6.mol

Synonyms:2,6-Di(1H-imidazol-1-yl)pyridine;39242-17-6;2,6-di(imidazol-1-yl)pyridine;2,6-bis(1-iMidazoly)pyridine;2,6-Bis(1-imidazolyl)pyridine;YSWG576;SCHEMBL10066877;2,6-bis(imidazol-1-yl)pyridine;DTXSID00477758;MFCD23103190;2,6-Di(1H-imidazol-1-yl) pyridine;AKOS022174935;AS-75513;CS-0110415;D97566;A873679

Chemical Property of 2,6-Di(1H-imidazol-1-yl)pyridine

Chemical Property:

• PSA: 48.53000
• LogP: 1.45300
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• XLogP3: 1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 211.08579531
• Heavy Atom Count: 16
• Complexity: 212

Purity/Quality:

97% ^*data from raw suppliers

2,6-Di(1H-imidazol-1-yl)pyridine 98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CC(=NC(=C1)N2C=CN=C2)N3C=CN=C3

Technology Process of 2,6-Di(1H-imidazol-1-yl)pyridine

There total 5 articles about 2,6-Di(1H-imidazol-1-yl)pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

1H-imidazole (288-32-4) + 2,6-Dibromopyridine (626-05-1) → 2,6-bis(1-imidazolyl)pyridine (39242-17-6)

Guidance literature:

With copper(l) iodide; potassium carbonate; L-proline; In dimethyl sulfoxide; at 90 ℃; for 12h;

DOI:10.1038/nchem.597

Reference yield: 88.0%

1H-imidazole (288-32-4) + 2,6-difluoro pyridine (1513-65-1) → 2,6-bis(1-imidazolyl)pyridine (39242-17-6)

Guidance literature:

at 90 - 120 ℃; for 35h;

DOI:10.1002/anie.200701486

Reference yield: 85.0%

1H-imidazole (288-32-4) + 2,6-dichloropyridine (2402-78-0) → 2,6-bis(1-imidazolyl)pyridine (39242-17-6)

Guidance literature:

With potassium hydroxide; tetrabutylammomium bromide; at 80 ℃; for 2h;

DOI:10.1016/S0022-328X(00)00715-4

upstream raw materials:

1H-imidazole

2,6-difluoro pyridine

2,6-dichloropyridine

2,6-Dibromopyridine