Ethyl 6-(4-methylphenyl)imidazo[2,1-b]thiazole-3-carboxylate

Base Information

Chemical Name:Ethyl 6-(4-methylphenyl)imidazo[2,1-b]thiazole-3-carboxylate
CAS No.:393107-90-9
Molecular Formula:C15H14N2O2S
Molecular Weight:286.34900
Hs Code.:
DSSTox Substance ID:DTXSID401184346
Mol file:393107-90-9.mol

Synonyms:DTXSID401184346;Ethyl 6-(4-methylphenyl)imidazo[2,1-b]thiazole-3-carboxylate;393107-90-9

Suppliers and Price of Ethyl 6-(4-methylphenyl)imidazo[2,1-b]thiazole-3-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of Ethyl 6-(4-methylphenyl)imidazo[2,1-b]thiazole-3-carboxylate

Chemical Property:

PSA：71.84000
LogP:3.54790
XLogP3:4.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:286.07759887
Heavy Atom Count:20
Complexity:358

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1=CSC2=NC(=CN12)C3=CC=C(C=C3)C

Technology Process of Ethyl 6-(4-methylphenyl)imidazo[2,1-b]thiazole-3-carboxylate

There total 4 articles about Ethyl 6-(4-methylphenyl)imidazo[2,1-b]thiazole-3-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

: 3-ethoxycarbonyl-6-p-tolyl-7H-imidazo[2,1-b]thiazol-4-ylium; bromide

: 393107-90-9
6-p-tolyl-imidazo[2,1-b]thiazole-3-carboxylic acid ethyl ester

Guidance literature:: With sodium carbonate; In water;

Reference yield:

: 5398-36-7
2-aminothiazole-4-carboxylate

: 393107-90-9
6-p-tolyl-imidazo[2,1-b]thiazole-3-carboxylic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 60 percent / ethanol / 16 h / Heating

2: 74 percent / sodium carbonate / H₂O

With sodium carbonate; In ethanol; water;

Reference yield:

: 619-41-0
4-(bromoacetyl)toluene

: 393107-90-9
6-p-tolyl-imidazo[2,1-b]thiazole-3-carboxylic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 60 percent / ethanol / 16 h / Heating

2: 74 percent / sodium carbonate / H₂O

With sodium carbonate; In ethanol; water;