Ursodeoxycholic acid sodium

Base Information

Chemical Name:Ursodeoxycholic acid sodium
CAS No.:2898-95-5
Molecular Formula:C₂₄H₃₉O₄*Na
Molecular Weight:414.561
Hs Code.:
European Community (EC) Number:684-592-1
Mol file:2898-95-5.mol

Synonyms:ursodeoxycholic acid sodium;2898-95-5;SCHEMBL2547966;AKOS040749729

Suppliers and Price of Ursodeoxycholic acid sodium

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
SodiumUrsodeoxycholate
25g
$ 255.00

Cayman Chemical
Ursodeoxycholic Acid (sodium salt) ≥98%
1g
$ 182.00

Cayman Chemical
Ursodeoxycholic Acid (sodium salt) ≥98%
500mg
$ 104.00

Cayman Chemical
Ursodeoxycholic Acid (sodium salt) ≥98%
250mg
$ 65.00

Cayman Chemical
Ursodeoxycholic Acid (sodium salt) ≥98%
5g
$ 650.00

AK Scientific
Sodiumursodeoxycholatehydrate
5g
$ 651.00

Total 14 raw suppliers

Chemical Property of Ursodeoxycholic acid sodium

Chemical Property:

Vapor Pressure:2.98E-14mmHg at 25°C
Boiling Point:547.1°C at 760 mmHg
Flash Point:298.8°C
PSA：80.59000
LogP:3.14320
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:415.28242903
Heavy Atom Count:29
Complexity:605

Purity/Quality:

97% ^*data from raw suppliers

SodiumUrsodeoxycholate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(CCC(=O)O)C1CCC2C1(CCC3C2C(CC4C3(CCC(C4)O)C)O)C.[Na]
Isomeric SMILES:C[C@H](CCC(=O)O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2[C@H](C[C@H]4[C@@]3(CC[C@H](C4)O)C)O)C.[Na]
Description Ursodeoxycholic acid (UDCA) is a secondary bile acid formed via epimerization of chenodeoxycholic acid (CDCA; ). UDCA is also a metabolite of lithocholic acid (LCA; ) in human liver microsomes. It inhibits taurocholic acid uptake in HeLa cells expressing recombinant sodium/taurocholate cotransporting polypeptide (NTCP) with an IC50 value of 3.6 μM. UDCA (50 μM) inhibits apoptosis induced by deoxycholic acid (DCA; Item Nos. 20756 | 18231) or ethanol in primary rat hepatocytes. Dietary administration of UDCA blocks DCA-induced increases in the number of TUNEL-positive hepatocytes in rats. Formulations containing UDCA have been used in the treatment of primary biliary cirrhosis.

Technology Process of Ursodeoxycholic acid sodium

There total 1 articles about Ursodeoxycholic acid sodium which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 128-13-2
ursodeoxycholic acid

: 2646-38-0,2898-95-5,31687-63-5,31687-65-7,108609-27-4
3,7-dihydroxycholan-24-oic acid, monosodium salt

Guidance literature:: With sodium hydroxide; In ethanol; water; at 20 ℃; for 1h;
DOI:10.1016/j.ejmech.2012.03.020

Reference yield:

: 2646-38-0,2898-95-5,31687-63-5,31687-65-7,108609-27-4
3,7-dihydroxycholan-24-oic acid, monosodium salt

: 77060-26-5
3-keto-7β-hydroxy-5β-cholan-24-oic acid

Guidance literature:: With DL-dithiothreitol; NAD; In water; ethyl acetate; for 40h; Yield given; Ambient temperature; 3α-hydroxysteroid dehydrogenase, puryvate/lactic dehydrogenase, serum albumin, potassium phosphate buffer pH=8.5;
DOI:10.1021/jo00236a018