Technology Process of dibenzo[b,d]furan-3-ylboronic acid
There total 9 articles about dibenzo[b,d]furan-3-ylboronic acid which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
3-bromodibenzofuran;
With
n-butyllithium;
In
tetrahydrofuran; acetone;
at -60 - -50 ℃;
for 1h;
Inert atmosphere;
Triisopropyl borate;
In
tetrahydrofuran; acetone;
at -45 - 20 ℃;
for 20h;
Inert atmosphere;
water;
With
hydrogenchloride;
In
tetrahydrofuran; acetone;
at 10 - 20 ℃;
for 4h;
Inert atmosphere;
- Guidance literature:
-
3-bromodibenzofuran;
With
n-butyllithium;
In
tetrahydrofuran; hexane;
at -63 ℃;
for 2.5h;
Inert atmosphere;
Triisopropyl borate;
In
tetrahydrofuran; hexane;
at -65 - 20 ℃;
for 3.3h;
Inert atmosphere;
With
hydrogenchloride;
In
tetrahydrofuran; hexane; water;
at 20 ℃;
for 1h;
Inert atmosphere;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: ammonium chloride; iron / water; isopropyl alcohol / 20 °C
1.2: 20 °C / Reflux
2.1: hydrogen bromide; sodium nitrite / water / -10 - 5 °C
2.2: 18 h / -5 - 40 °C
3.1: n-butyllithium / tetrahydrofuran; acetone / 1 h / -60 - -50 °C / Inert atmosphere
3.2: 20 h / -45 - 20 °C / Inert atmosphere
3.3: 4 h / 10 - 20 °C / Inert atmosphere
With
n-butyllithium; hydrogen bromide; iron; ammonium chloride; sodium nitrite;
In
tetrahydrofuran; water; isopropyl alcohol; acetone;
