(R)-tert-Butyl 3-amino-4-phenylbutanoate

Base Information

Chemical Name:(R)-tert-Butyl 3-amino-4-phenylbutanoate
CAS No.:166023-31-0
Molecular Formula:C14H21NO2
Molecular Weight:235.32
Hs Code.:29163990
DSSTox Substance ID:DTXSID501247000
Mol file:166023-31-0.mol

Synonyms:166023-31-0;(R)-tert-Butyl 3-amino-4-phenylbutanoate;tert-butyl (3R)-3-amino-4-phenylbutanoate;1,1-Dimethylethyl (3R)-3-amino-4-phenylbutanoate;MFCD00798307;T-BUTYL(3R)-3-AMINO-4-PHENYLBUTANOATE;tert-Butyl (R)-3-Amino-4-phenylbutanoate;tert-Butyl (3R)-3-amino-4-phenyl-butanoate;(R)-tert-Butyl3-amino-4-phenylbutanoate;SCHEMBL2295757;DTXSID501247000;AKOS016844148;AS-39937;CS-0272759;EN300-6747377;A810689;1,1-Dimethylethyl (betaR)-beta-aminobenzenebutanoate;Benzenebutanoic acid,b-amino-,1,1-dimethylethyl ester,(br)-

Suppliers and Price of (R)-tert-Butyl 3-amino-4-phenylbutanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
(R)-tert-Butyl3-amino-4-phenylbutanoate 95+%
1g
$ 972.00

Chemenu
(R)-tert-Butyl3-amino-4-phenylbutanoate 95%
1g
$ 916.00

American Custom Chemicals Corporation
1,1-DIMETHYLETHYL (3R)-3-AMINO-4-PHENYLBUTANOATE 95.00%
100MG
$ 727.65

American Custom Chemicals Corporation
1,1-DIMETHYLETHYL (3R)-3-AMINO-4-PHENYLBUTANOATE 95.00%
1G
$ 1697.85

Alichem
(R)-tert-Butyl3-amino-4-phenylbutanoate
5g
$ 2556.72

Alichem
(R)-tert-Butyl3-amino-4-phenylbutanoate
1g
$ 871.00

AHH
t-Butyl(3R)-3-amino-4-phenylbutanoate 97%
1g
$ 412.00

Acrotein
(R)-tert-Butyl3-amino-4-phenylbutanoate 97%
0.25g
$ 201.67

ACHEMBLOCK
(R)-tert-Butyl3-amino-4-phenylbutanoate 95%
250MG
$ 275.00

Total 17 raw suppliers

Chemical Property of (R)-tert-Butyl 3-amino-4-phenylbutanoate

Chemical Property:

Appearance/Colour:White or slightly yellow low melting solid
Vapor Pressure:9.15E-05mmHg at 25°C
Boiling Point:339.5 °C at 760 mmHg
PKA:7.98±0.10(Predicted)
Flash Point:187 °C
PSA：52.32000
Density:1.028 g/cm³
LogP:2.98850
Storage Temp.:Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
XLogP3:2.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:6
Exact Mass:235.157228913
Heavy Atom Count:17
Complexity:239

Purity/Quality:

97% ^*data from raw suppliers

(R)-tert-Butyl3-amino-4-phenylbutanoate 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Safety Statements: 24/25

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)CC(CC1=CC=CC=C1)N
Isomeric SMILES:CC(C)(C)OC(=O)C[C@@H](CC1=CC=CC=C1)N

Technology Process of (R)-tert-Butyl 3-amino-4-phenylbutanoate

There total 5 articles about (R)-tert-Butyl 3-amino-4-phenylbutanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: (3R,αR)-tert-butyl 3-(N-benzyl-N-α-methylbenzyl)amino-4-phenylbutanoate

: 166023-31-0
tert-butyl (3R)-3-amino-4-phenylbutanoate

Guidance literature:: (3R,αR)-tert-butyl 3-(N-benzyl-N-α-methylbenzyl)amino-4-phenylbutanoate; With 10 wt% Pd(OH)2 on carbon; hydrogen; acetic acid; In methanol; water; at 0 - 20 ℃; for 72h;

With sodium hydrogencarbonate; In methanol; water;
DOI:10.1055/s-0034-1380675

Reference yield:

: 87512-35-4
tert-butyl 3-amino-4-phenylbut-2-enoate

: 166023-31-0
tert-butyl (3R)-3-amino-4-phenylbutanoate

: 120686-17-1
(S)-3-amino-4-phenylbutyric acid tert-butyl ester

Guidance literature:: With (2S,1'S,2'R)-1-formyl-piperidine-2-carboxylic acid (2-methoxymethoxy-1,2-diphenyl-ethyl)-amide; trichlorosilane; water; In dichloromethane; at 0 ℃; for 24h; Overall yield = 99 %; enantioselective reaction; Inert atmosphere;
DOI:10.1002/adsc.201501061

Reference yield:

: t-butyl 3-benzylacrylate

: 166023-31-0
tert-butyl (3R)-3-amino-4-phenylbutanoate

Guidance literature:: Multi-step reaction with 2 steps

1: lithium benzyl-(R)-1-phenylethylamide / tetrahydrofuran / 2 h / -78 °C

2: acetic acid; hydrogen; 10 wt% Pd(OH)2 on carbon / methanol; water / 72 h / 0 - 20 °C

With 10 wt% Pd(OH)2 on carbon; hydrogen; acetic acid; lithium benzyl-(R)-1-phenylethylamide; In tetrahydrofuran; methanol; water;
DOI:10.1055/s-0034-1380675