3-Chloro-4-hydroxybenzohydrazide

Base Information

• Chemical Name: 3-Chloro-4-hydroxybenzohydrazide
• CAS No.: 39634-98-5
• Molecular Formula: C7H7ClN2O2
• Molecular Weight: 186.598
• European Community (EC) Number: 964-809-9
• Mol file: 39634-98-5.mol

Synonyms:3-CHLORO-4-HYDROXYBENZOHYDRAZIDE;39634-98-5;3-chloro-4-hydroxybenzoic acid hydrazide;SCHEMBL1363239;UGUNVMQWBRYTIE-UHFFFAOYSA-N;3-chloro-4-hydroxybenzoic hydrazide;MFCD09809436;AKOS000160033;LS-11805;3-chloro-4-hydroxy benzoic acid hydrazide;CS-0261196;EN300-77612

Chemical Property of 3-Chloro-4-hydroxybenzohydrazide

Chemical Property:

• PSA: 75.35000
• LogP: 1.74030
• XLogP3: 1
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 186.0196052
• Heavy Atom Count: 12
• Complexity: 177

Purity/Quality:

95% ^*data from raw suppliers

3-chloro-4-hydroxybenzohydrazide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CC(=C(C=C1C(=O)NN)Cl)O

Technology Process of 3-Chloro-4-hydroxybenzohydrazide

There total 3 articles about 3-Chloro-4-hydroxybenzohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

→ 3-chloro-4-hydroxybenzoic acid hydrazide (39634-98-5)

Guidance literature:

Reference yield: 60.0%

methyl 4-hydroxy-3-chlorobenzoate (3964-57-6) → 3-chloro-4-hydroxybenzoic acid hydrazide (39634-98-5)

Guidance literature:

With hydrazine; In ethanol; Heating;

DOI:10.1021/jm000547o

Reference yield:

C12H15ClN2O4 → 3-chloro-4-hydroxybenzoic acid hydrazide (39634-98-5)

Guidance literature:

deprotection;

DOI:10.1016/j.bmcl.2008.01.052

upstream raw materials:

methyl 4-hydroxy-3-chlorobenzoate

Downstream raw materials:

3-Chloro-4-hydroxybenzoic Acid (4-Hydroxy-1-naphthylmethylene)hydrazide

C₂₆H₂₇ClN₂O₆

C₂₄H₁₇ClF₃N₃O₂