1-[2-(2-Chlorophenyl)ethyl]piperidin-4-one

Base Information

Chemical Name:1-[2-(2-Chlorophenyl)ethyl]piperidin-4-one
CAS No.:39742-61-5
Molecular Formula:C13H16ClNO
Molecular Weight:237.729
Hs Code.:
DSSTox Substance ID:DTXSID10516768
Wikidata:Q82378332
Mol file:39742-61-5.mol

Synonyms:1-[2-(2-Chlorophenyl)ethyl]piperidin-4-one;39742-61-5;SCHEMBL11396959;N-o-chlorophenethyl-4-piperidone;DTXSID10516768;SIQFHAQBMXLXPR-UHFFFAOYSA-N

Suppliers and Price of 1-[2-(2-Chlorophenyl)ethyl]piperidin-4-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 1-[2-(2-Chlorophenyl)ethyl]piperidin-4-one

Chemical Property:

XLogP3:2.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:237.0920418
Heavy Atom Count:16
Complexity:234

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CCC1=O)CCC2=CC=CC=C2Cl

Technology Process of 1-[2-(2-Chlorophenyl)ethyl]piperidin-4-one

There total 3 articles about 1-[2-(2-Chlorophenyl)ethyl]piperidin-4-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1-[2-(2-Chloro-phenyl)-ethyl]-4-oxo-piperidine-3-carboxylic acid ethyl ester

: 39742-61-5
1-(o-chloro phenethyl)-4-piperidone

Guidance literature:: With hydrogenchloride; In water; isopropyl alcohol; at 20 - 130 ℃; for 6h; Yield given;
DOI:10.1021/jm00355a010

Reference yield:

: 13078-80-3
2-(2-chlorophenyl)ethanamine

: 39742-61-5
1-(o-chloro phenethyl)-4-piperidone

Guidance literature:: Multi-step reaction with 3 steps

1: 98.7 percent / acetic acid / 6 h / 60 °C

2: Na, propanol / 1 h / Heating

3: conc. HCl / propan-2-ol; H₂O / 6 h / 20 - 130 °C

With hydrogenchloride; propan-1-ol; sodium; acetic acid; In water; isopropyl alcohol;
DOI:10.1021/jm00355a010

Reference yield:

: 83605-17-8
N,N-bis(2-carbethoxyethyl)-2-chlorophenethylamine

: 39742-61-5
1-(o-chloro phenethyl)-4-piperidone

Guidance literature:: Multi-step reaction with 2 steps

1: Na, propanol / 1 h / Heating

2: conc. HCl / propan-2-ol; H₂O / 6 h / 20 - 130 °C

With hydrogenchloride; propan-1-ol; sodium; In water; isopropyl alcohol;
DOI:10.1021/jm00355a010