N-(3-methylphenyl)thiophene-2-carboxamide

Base Information

Chemical Name:N-(3-methylphenyl)thiophene-2-carboxamide
CAS No.:39880-79-0
Molecular Formula:C12H11NOS
Molecular Weight:217.291
Hs Code.:
DSSTox Substance ID:DTXSID701270677
Nikkaji Number:J1.855.871H
Mol file:39880-79-0.mol

Synonyms:N-(3-methylphenyl)thiophene-2-carboxamide;39880-79-0;2-thiophenecarboxamide,n-(3-methylphenyl)-;N-(3-methylphenyl)-2-thiophenecarboxamide;Thiophene-2-carboxamide, N-(3-methylphenyl)-;SCHEMBL12496157;N-m-tolylthiophene-2-carboxamide;DTXSID701270677;STK861410;AKOS001297508;Z27791211

Suppliers and Price of N-(3-methylphenyl)thiophene-2-carboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of N-(3-methylphenyl)thiophene-2-carboxamide

Chemical Property:

Melting Point:146 °C
Boiling Point:268.1±23.0 °C(Predicted)
PKA:12.65±0.70(Predicted)
PSA：57.34000
Density:1.248±0.06 g/cm3(Predicted)
LogP:3.38180
XLogP3:3.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:217.05613515
Heavy Atom Count:15
Complexity:232

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=CC=C1)NC(=O)C2=CC=CS2

Technology Process of N-(3-methylphenyl)thiophene-2-carboxamide

There total 9 articles about N-(3-methylphenyl)thiophene-2-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 5813-89-8
2-thiophenylcarboxamide

: 591-17-3
meta-bromotoluene

: 39880-79-0
N-(3-methylphenyl)thiophene-2-carboxamide

Guidance literature:: With bis[chloro(1,2,3-trihapto-allylbenzene)palladium(II)]; potassium hydroxide; tert-butyl XPhos; In ethanol; at 50 ℃; for 6h;
DOI:10.1021/acscatal.1c04641

Reference yield: 88.0%

: 5813-89-8
2-thiophenylcarboxamide

: 108-41-8
1-chloro-3-methylbenzene

: 39880-79-0
N-(3-methylphenyl)thiophene-2-carboxamide

Guidance literature:: With bis[chloro(1,2,3-trihapto-allylbenzene)palladium(II)]; potassium hydroxide; tert-butyl XPhos; In ethanol; at 50 ℃; for 6h;
DOI:10.1021/acscatal.1c04641

Reference yield: 80.0%

: 2-bromo-2,2-difluoro-N-(m-tolylphenyl)acetamide

: C₆H₉S₂⁽¹⁺⁾*CF₃O₃S^(1-)

: 39880-79-0
N-(3-methylphenyl)thiophene-2-carboxamide

Guidance literature:: With potassium fluoride; [ruthenium(II)(η⁶-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]₂; p-tert-Butylcalix[5]arene; copper(ll) bromide; magnesium chloride; for 11h; Inert atmosphere; Heating;
DOI:10.3390/molecules26102957