1-(2,4-Dihydroxyphenyl)-2-(4-hydroxy-3-methoxyphenyl)-ethanone

Base Information

Chemical Name:1-(2,4-Dihydroxyphenyl)-2-(4-hydroxy-3-methoxyphenyl)-ethanone
CAS No.:40456-49-3
Molecular Formula:C15H14O5
Molecular Weight:274.273
Hs Code.:
ChEMBL ID:CHEMBL1288698
DSSTox Substance ID:DTXSID40474584
Nikkaji Number:J2.386.341C
Wikidata:Q82304686

Synonyms:1-(2,4-Dihydroxyphenyl)-2-(4-hydroxy-3-methoxyphenyl)-ethanone;40456-49-3;SCHEMBL1245832;CHEMBL1288698;DTXSID40474584;VXAPZUPSWVIAQJ-UHFFFAOYSA-N

Suppliers and Price of 1-(2,4-Dihydroxyphenyl)-2-(4-hydroxy-3-methoxyphenyl)-ethanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 1-(2,4-Dihydroxyphenyl)-2-(4-hydroxy-3-methoxyphenyl)-ethanone

Chemical Property:

PSA：86.99000
LogP:2.23740
XLogP3:2.7
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:274.08412354
Heavy Atom Count:20
Complexity:332

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C=CC(=C1)CC(=O)C2=C(C=C(C=C2)O)O)O

Technology Process of 1-(2,4-Dihydroxyphenyl)-2-(4-hydroxy-3-methoxyphenyl)-ethanone

There total 4 articles about 1-(2,4-Dihydroxyphenyl)-2-(4-hydroxy-3-methoxyphenyl)-ethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 306-08-1
Homovanillic acid

: 108-46-3
recorcinol

: 40456-49-3
1-(2,4-dihydroxyphenyl)-2-(4'-hydroxy-3'-methoxyphenyl)ethanone

Guidance literature:: With boron trifluoride diethyl etherate; at 60 - 70 ℃; for 1h;

Reference yield:

: 29973-91-9
4-benzyloxy-3-methoxyphenylacetic acid

: 40456-49-3
1-(2,4-dihydroxyphenyl)-2-(4'-hydroxy-3'-methoxyphenyl)ethanone

Guidance literature:: Multi-step reaction with 2 steps

1: H₂ / 10percent Pd-C / aq. ethanol

2: 99 percent / BF₃*Et₂O / 1 h / 60 - 70 °C

With boron trifluoride diethyl etherate; hydrogen; palladium on activated charcoal; In ethanol;

Reference yield:

: 16209-54-4
methyl 4-benzyloxy-3-methoxyphenylethanoate

: 40456-49-3
1-(2,4-dihydroxyphenyl)-2-(4'-hydroxy-3'-methoxyphenyl)ethanone

Guidance literature:: Multi-step reaction with 3 steps

1: 10percent KOH / methanol; H₂O

2: H₂ / 10percent Pd-C / aq. ethanol

3: 99 percent / BF₃*Et₂O / 1 h / 60 - 70 °C

With potassium hydroxide; boron trifluoride diethyl etherate; hydrogen; palladium on activated charcoal; In methanol; ethanol; water;