2(1H)-Quinolinone, 5-methyl-

Base Information

Chemical Name:2(1H)-Quinolinone, 5-methyl-
CAS No.:4053-33-2
Molecular Formula:C10H9NO
Molecular Weight:159.188
Hs Code.:
Mol file:4053-33-2.mol

Synonyms:5-Methyl-carbostyryl;5-Methyl-1H-quinolin-2-one;1,2-Dihydro-5-methylquinolin-2-one;5-Methylcarbostyril;5-methylquinolin-2(1H)-one;

Suppliers and Price of 2(1H)-Quinolinone, 5-methyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Alichem
2-Hydroxy-5-methylquinoline
1g
$ 1961.61

Alichem
2-Hydroxy-5-methylquinoline
250mg
$ 747.24

AccelPharmtech
5-methyl-2(1H)-Quinolinone 97.00%
25G
$ 4010.00

AccelPharmtech
5-methyl-2(1H)-Quinolinone 97.00%
1G
$ 1940.00

Total 4 raw suppliers

Chemical Property of 2(1H)-Quinolinone, 5-methyl-

Chemical Property:

Melting Point:221 - 223 °C
PSA：32.86000
LogP:1.83650

Purity/Quality:

95% ^*data from raw suppliers

2-Hydroxy-5-methylquinoline ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2(1H)-Quinolinone, 5-methyl-

There total 13 articles about 2(1H)-Quinolinone, 5-methyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

: 4053-41-2
5-methylquinoline 1-oxide

: 4053-33-2
5-methylquinolin-2-(1H)-one

Guidance literature:: With oxygen; In methanol; at 20 ℃; for 0.25h; Irradiation;
DOI:10.1021/jacs.6b03221

Reference yield: 17.0%

: 23980-96-3
(E)-N-(3-methylphenyl)-3-ethoxypropenamide

: 4053-33-2
5-methylquinolin-2-(1H)-one

Guidance literature:: With hydrogenchloride; In water; at 20 - 40 ℃; for 1h;
DOI:10.1371/journal.pone.0113705

Reference yield:

: 4964-71-0
5-bromoquinoline

: 4053-33-2
5-methylquinolin-2-(1H)-one

Guidance literature:: Multi-step reaction with 3 steps

1.1: n-butyllithium / tetrahydrofuran; hexane / 0.25 h / -78 °C / Inert atmosphere; Schlenk technique

1.2: 0.5 h / -78 - 20 °C / Inert atmosphere; Schlenk technique

2.1: 3-chloro-benzenecarboperoxoic acid / chloroform / 1 h / 20 °C

3.1: oxygen / methanol / 0.25 h / 20 °C / Irradiation

With n-butyllithium; oxygen; 3-chloro-benzenecarboperoxoic acid; In tetrahydrofuran; methanol; hexane; chloroform;
DOI:10.1021/jacs.6b03221