1-Phenyl-2,2-dimethyl-3-iodopropane

Base Information

• Chemical Name: 1-Phenyl-2,2-dimethyl-3-iodopropane
• CAS No.: 40548-64-9
• Molecular Formula: C11H15I
• Molecular Weight: 274.145
• Mol file: 40548-64-9.mol

Synonyms:2-Benzyl-2-methyl-1-jodpropan;2,2-dimethyl-1-iodo-3-phenylpropane;3-iodo-2,2-dimethyl-1-phenylpropane;(3-iodo-2,2-dimethylpropyl)benzene;2-methyl-2-benzyl-1-iodopropane;

Chemical Property of 1-Phenyl-2,2-dimethyl-3-iodopropane

Chemical Property:

• PSA: 0.00000
• LogP: 3.69030

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-Phenyl-2,2-dimethyl-3-iodopropane

There total 3 articles about 1-Phenyl-2,2-dimethyl-3-iodopropane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,2-dimethyl-3-phenyl-1-propyl p-toluenesulfonate (14248-19-2) → 3-iodo-2,2-dimethyl-1-phenylpropane (40548-64-9)

Guidance literature:

With potassium iodide; In N,N-dimethyl-formamide;

Reference yield:

2,2-dimethyl-3-phenyl-propionic acid isobutyl ester (40548-66-1) → 3-iodo-2,2-dimethyl-1-phenylpropane (40548-64-9)

Guidance literature:

Multi-step reaction with 2 steps

1: LiAlH₄

2: (i) MeSO₂Cl, (ii) KI

With lithium aluminium tetrahydride;

DOI:10.1021/jo00956a004

Reference yield:

2,2-dimethyl-3-phenyl-1-propanol (13351-61-6) → 3-iodo-2,2-dimethyl-1-phenylpropane (40548-64-9)

Guidance literature:

Multistep reaction; (i) MeSO₂Cl, (ii) KI;

DOI:10.1021/jo00956a004

upstream raw materials:

2,2-dimethyl-3-phenyl-1-propanol

2,2-dimethyl-3-phenyl-1-propyl p-toluenesulfonate

2,2-dimethyl-3-phenyl-propionic acid isobutyl ester

Downstream raw materials:

1-(2,2-Dimethyl-3-phenylpropyl)-2-methylbenzene

1,6-Diphenyl-2,2,5,5-tetramethylhexane

2,2-dimethyl-1-phenylbutane

(2,2-dimethyl-1-propyl)benzene

Refernces