Technology Process of Benzene,
1-[[4-[(2,5-dipropoxyphenyl)ethynyl]-2,5-dipropoxyphenyl]ethynyl]-4-[[4-[(
4-ethynyl-2,5-dipropoxyphenyl)ethynyl]-2,5-dipropoxyphenyl]ethynyl]-2,5-
dipropoxy-
There total 18 articles about Benzene,
1-[[4-[(2,5-dipropoxyphenyl)ethynyl]-2,5-dipropoxyphenyl]ethynyl]-4-[[4-[(
4-ethynyl-2,5-dipropoxyphenyl)ethynyl]-2,5-dipropoxyphenyl]ethynyl]-2,5-
dipropoxy- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 8 steps
1: 76 percent / Br2; NaOAc / acetic acid / 12 h / 20 °C
2: 77 percent / iodine; KIO3; H2SO4 / H2O; acetic acid; CCl4 / 5 h / Heating
3: 85 percent / PPh3; piperidine / PdCl2(PPh4)2/CuI / 12 h
4: 84 percent / PPh3; piperidine / PdCl2(PPh4)2/CuI / 12 h
5: 65 percent / K2CO3 / methanol; tetrahydrofuran / 1 h
6: 39 percent / PPh3; piperidine / PdCl2(PPh4)2/CuI / 6 h / 60 °C
7: 84 percent / PPh3; piperidine / PdCl2(PPh4)2/CuI / 18 h / 60 - 80 °C
8: 94 percent / nBU4NF / tetrahydrofuran / 0.33 h
With
piperidine; potassium iodate; sulfuric acid; tetrabutyl ammonium fluoride; bromine; iodine; sodium acetate; potassium carbonate; triphenylphosphine;
bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide;
In
tetrahydrofuran; methanol; tetrachloromethane; water; acetic acid;
3: Hagihara-Sonogashira reaction / 4: Hagihara-Sonogashira reaction / 6: Hagihara-Sonogashira reaction / 7: Hagihara-Sonogashira reaction;
DOI:10.1002/1099-0690(200112)2001:23<4431::aid-ejoc4431>3.0.co;2-j
- Guidance literature:
-
Multi-step reaction with 9 steps
1: 85 percent / KOH / ethanol / 2 h / Heating
2: 76 percent / Br2; NaOAc / acetic acid / 12 h / 20 °C
3: 77 percent / iodine; KIO3; H2SO4 / H2O; acetic acid; CCl4 / 5 h / Heating
4: 85 percent / PPh3; piperidine / PdCl2(PPh4)2/CuI / 12 h
5: 84 percent / PPh3; piperidine / PdCl2(PPh4)2/CuI / 12 h
6: 65 percent / K2CO3 / methanol; tetrahydrofuran / 1 h
7: 39 percent / PPh3; piperidine / PdCl2(PPh4)2/CuI / 6 h / 60 °C
8: 84 percent / PPh3; piperidine / PdCl2(PPh4)2/CuI / 18 h / 60 - 80 °C
9: 94 percent / nBU4NF / tetrahydrofuran / 0.33 h
With
piperidine; potassium iodate; potassium hydroxide; sulfuric acid; tetrabutyl ammonium fluoride; bromine; iodine; sodium acetate; potassium carbonate; triphenylphosphine;
bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide;
In
tetrahydrofuran; methanol; tetrachloromethane; ethanol; water; acetic acid;
4: Hagihara-Sonogashira reaction / 5: Hagihara-Sonogashira reaction / 7: Hagihara-Sonogashira reaction / 8: Hagihara-Sonogashira reaction;
DOI:10.1002/1099-0690(200112)2001:23<4431::aid-ejoc4431>3.0.co;2-j
![1-[4-(2,5-dipropoxyphenylethynyl)-2,5-dipropoxyphenylethynyl]-4-[2,5-dipropoxy-4-(2,5-dipropoxy-4-triisopropylsilylethynylphenylethynyl)phenylethynyl]-2,5-dipropoxybenzene](/Databaselist/images/loading.webp)
