4-(2-Hydroxyethyl)morpholin-3-one

Base Information

Chemical Name:4-(2-Hydroxyethyl)morpholin-3-one
CAS No.:41036-01-5
Molecular Formula:C6H11NO3
Molecular Weight:145.158
Hs Code.:2934999090
DSSTox Substance ID:DTXSID40571007
Wikidata:Q82458585
Mol file:41036-01-5.mol

Synonyms:4-(2-HYDROXYETHYL)MORPHOLIN-3-ONE;41036-01-5;3-Morpholinone, 4-(2-hydroxyethyl)-;SCHEMBL824835;DTXSID40571007;NLQNYAFMZKEJEO-UHFFFAOYSA-N;4-(2-hydroxyethyl)3-morpholinone;4-(2-hydroxyethyl)-3-morpholinone;AKOS023556773;4-(2-Hydroxy-ethyl)-morpholin-3-one;EN300-130287;A825406;F8889-2494;Z1323533212

Suppliers and Price of 4-(2-Hydroxyethyl)morpholin-3-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-(2-hydroxyethyl)morpholin-3-one
50mg
$ 220.00

TRC
4-(2-hydroxyethyl)morpholin-3-one
10mg
$ 65.00

Matrix Scientific
4-(2-Hydroxyethyl)morpholin-3-one 97%
1g
$ 1213.00

AK Scientific
4-(2-Hydroxyethyl)morpholin-3-one
100mg
$ 518.00

Total 7 raw suppliers

Chemical Property of 4-(2-Hydroxyethyl)morpholin-3-one

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:340.746oC at 760 mmHg
PKA:14.39±0.10(Predicted)
Flash Point:159.878oC
PSA：49.77000
Density:1.208g/cm3
LogP:-1.22460
XLogP3:-1.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:145.07389321
Heavy Atom Count:10
Complexity:126

Purity/Quality:

97% ^*data from raw suppliers

4-(2-hydroxyethyl)morpholin-3-one ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1COCC(=O)N1CCO

Technology Process of 4-(2-Hydroxyethyl)morpholin-3-one

There total 6 articles about 4-(2-Hydroxyethyl)morpholin-3-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 96-34-4
methyl chloroacetate

: 41036-01-5
4-(2-hydroxyethyl)morpholin-3-one

Guidance literature:: 2,2'-iminobis[ethanol]; With potassium tert-butylate; In toluene; at 75 ℃; for 1h;

methyl chloroacetate; In toluene; at 75 ℃; for 2h;

Reference yield: 70.0%

: 892871-54-4
4-(2-(benzyloxy)ethyl)morpholin-3-one

: 41036-01-5
4-(2-hydroxyethyl)morpholin-3-one

Guidance literature:: With hydrogen; 5%-palladium/activated carbon; In ethanol; under 3102.97 Torr;

Reference yield: 58.0%

: 622-40-2
2-(morpholin-4-yl)ethanol

: 41036-01-5
4-(2-hydroxyethyl)morpholin-3-one

Guidance literature:: 2-(morpholin-4-yl)ethanol; With sodium dihydrogenphosphate; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; In acetonitrile; at 0 ℃; for 0.0833333h;

With sodium hypochlorite; sodium chlorite; In water; acetonitrile;
DOI:10.1021/acs.joc.8b02564