4-Isothiazolecarbonitrile, 5-amino-3-(1-methylethyl)-

Base Information

• Chemical Name: 4-Isothiazolecarbonitrile, 5-amino-3-(1-methylethyl)-
• CAS No.: 41808-37-1
• Molecular Formula: C₇H₉N₃S
• Molecular Weight: 167.235
• Mol file: 41808-37-1.mol

Synonyms:5-Amino-4-cyano-3-isopropylisothiazol;5-amino-4-cyano-3-isopropylisothiazole;5-Amino-3-isopropyl-isothiazole-4-carbonitrile;

Chemical Property of 4-Isothiazolecarbonitrile, 5-amino-3-(1-methylethyl)-

Chemical Property:

• Melting Point: 133 - 136 °C
• PSA: 90.94000
• LogP: 2.30158

Purity/Quality:

97% ^*data from raw suppliers

5-Amino-3-isopropylisothiazole-4-carbonitrile 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-Isothiazolecarbonitrile, 5-amino-3-(1-methylethyl)-

There total 6 articles about 4-Isothiazolecarbonitrile, 5-amino-3-(1-methylethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-Amino-2-cyano-4-methyl-2-pententhiocarboxamid (41808-32-6) → 5-Amino-4-cyano-3-isopropylisothiazol (41808-37-1)

Guidance literature:

With dihydrogen peroxide; In methanol; at 10 - 20 ℃; for 16h;

Reference yield:

3-amino-2-cyano-4-methyl-2-pentenethioamide → 5-Amino-4-cyano-3-isopropylisothiazol (41808-37-1)

Guidance literature:

With dihydrogen peroxide; In ethanol; water;

Reference yield:

2-amino-1,1-dicyano-3-methylbut-1-ene (41808-27-9) → 5-Amino-4-cyano-3-isopropylisothiazol (41808-37-1)

Guidance literature:

Multi-step reaction with 2 steps

1: pyridine; triethylamine / ethanol; water

2: dihydrogen peroxide / ethanol; water

With pyridine; dihydrogen peroxide; triethylamine; In ethanol; water;

upstream raw materials:

2-amino-1,1-dicyano-3-methylbut-1-ene

(1-hydroxy-2-methylpropylidene)methane-1,1-dicarbonitrile

(1-chloro-2-methylpropylidene)methane-1,1-dicarbonitrile

3-Amino-2-cyano-4-methyl-2-pententhiocarboxamid