2-[3-(Trifluoromethyl)phenyl]hydrazine-1-carboxamide

Base Information

Chemical Name:2-[3-(Trifluoromethyl)phenyl]hydrazine-1-carboxamide
CAS No.:42158-58-7
Molecular Formula:C₈H₈F₃N₃O
Molecular Weight:219.166
Hs Code.:
DSSTox Substance ID:DTXSID60523609
Wikidata:Q82389814
Mol file:42158-58-7.mol

Synonyms:2-[3-(Trifluoromethyl)phenyl]hydrazine-1-carboxamide;42158-58-7;SCHEMBL11798167;DTXSID60523609;LJTDVJOPLMXKMS-UHFFFAOYSA-N

Suppliers and Price of 2-[3-(Trifluoromethyl)phenyl]hydrazine-1-carboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-[3-(Trifluoromethyl)phenyl]hydrazine-1-carboxamide

Chemical Property:

XLogP3:1.7
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:219.06194637
Heavy Atom Count:15
Complexity:232

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC(=C1)NNC(=O)N)C(F)(F)F

Technology Process of 2-[3-(Trifluoromethyl)phenyl]hydrazine-1-carboxamide

There total 1 articles about 2-[3-(Trifluoromethyl)phenyl]hydrazine-1-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 25.0%

: 506-68-3
bromocyane

: 368-78-5
3-(trifluoromethyl)phenylhydrazine

: 42158-58-7
C₈H₈F₃N₃O

Guidance literature:: With sodium hydroxide; In ethanol; for 20h; Ambient temperature;

Reference yield: 91.0%

: 42158-58-7
C₈H₈F₃N₃O

: 122-51-0
orthoformic acid triethyl ester

: 42158-59-8
1-(3-trifluoromethyl-phenyl)-1,2-dihydro-[1,2,4]triazol-3-one

Guidance literature:: With toluene-4-sulfonic acid; for 16h; steam bath temperature;

Reference yield:

: 42158-58-7
C₈H₈F₃N₃O

: 110607-57-3
3-(1-ethoxycarbonylethoxy)-1-(3-trifluoromethylphenyl)-1,2,4-1H-triazole

Guidance literature:: Multi-step reaction with 2 steps

1: 91 percent / p-toluenesulfonic acid / 16 h / steam bath temperature

2: 78 percent / sodium methoxide / dimethylsulfoxide; methanol / 4 h / at steam bath temperature

With sodium methylate; toluene-4-sulfonic acid; In methanol; dimethyl sulfoxide;