1-(4-Bromo-benzyl)-4-methanesulfonyl-piperazine

Base Information

Chemical Name:1-(4-Bromo-benzyl)-4-methanesulfonyl-piperazine
CAS No.:423743-43-5
Molecular Formula:C12H17BrN2O2S
Molecular Weight:333.249
Hs Code.:
DSSTox Substance ID:DTXSID80354937
Wikidata:Q82133446
Mol file:423743-43-5.mol

Synonyms:1-(4-Bromo-benzyl)-4-methanesulfonyl-piperazine;423743-43-5;CBMicro_039991;1-(4-bromobenzyl)-4-methanesulfonylpiperazine;Cambridge id 5992377;Oprea1_372543;Oprea1_735575;DTXSID80354937;STK325368;AKOS000548470;BIM-0039912.P001;1-(4-bromobenzyl)-4-(methylsulfonyl)piperazine;AB00101787-01

Suppliers and Price of 1-(4-Bromo-benzyl)-4-methanesulfonyl-piperazine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1-(4-Bromo-benzyl)-4-methanesulfonyl-piperazine

Chemical Property:

XLogP3:1.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:332.01941
Heavy Atom Count:18
Complexity:353

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CS(=O)(=O)N1CCN(CC1)CC2=CC=C(C=C2)Br

Technology Process of 1-(4-Bromo-benzyl)-4-methanesulfonyl-piperazine

There total 1 articles about 1-(4-Bromo-benzyl)-4-methanesulfonyl-piperazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 55276-43-2
4-methanesulfonylpiperazine

: 589-15-1
1-bromomethyl-4-bromobenzene

: 423743-43-5
1-(4-bromobenzyl)-4-methanesulfonylpiperazine

Guidance literature:: With triethylamine; In tetrahydrofuran; for 3h;
DOI:10.1021/jo0480545

Reference yield: 100.0%

: 423743-43-5
1-(4-bromobenzyl)-4-methanesulfonylpiperazine

: 5350-57-2
benzophenone hydrazone

: 850170-96-6
N-benzhydrylidene-N'-[4-(4-methanesulfonylpiperazin-1-ylmethyl)phenyl]hydrazine

Guidance literature:: With 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; sodium t-butanolate; palladium diacetate; In toluene; at 105 ℃; for 4h;
DOI:10.1021/jo0480545

Reference yield: 84.0%

: 423743-43-5
1-(4-bromobenzyl)-4-methanesulfonylpiperazine

: 75927-49-0
pinacol vinylboronate

: (E)-1-(methylsulfonyl)-4-(4-(2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)vinyl)benzyl)piperazine

Guidance literature:: With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; N-ethyl-N,N-diisopropylamine; tri tert-butylphosphoniumtetrafluoroborate; In toluene; at 95 ℃; for 3h; Inert atmosphere;
DOI:10.1039/C6NJ03984G