1,8,15,22-Tetraazacyclooctacosane-2,7,16,21-tetrone

Base Information

• Chemical Name: 1,8,15,22-Tetraazacyclooctacosane-2,7,16,21-tetrone
• CAS No.: 4238-35-1
• Molecular Formula: C24H44N4O4
• Molecular Weight: 452.638
• Mol file: 4238-35-1.mol

Synonyms:

Chemical Property of 1,8,15,22-Tetraazacyclooctacosane-2,7,16,21-tetrone

Chemical Property:

Purity/Quality:

99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1,8,15,22-Tetraazacyclooctacosane-2,7,16,21-tetrone

There total 1 articles about 1,8,15,22-Tetraazacyclooctacosane-2,7,16,21-tetrone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 37.0%

1,6-Hexanediamine (124-09-4) + 1,6-Bis-(2-thioxo-thiazolidin-3-yl)-hexane-1,6-dione (74058-83-6) → 1,8-diaza-cyclotetradecane-2,7-dione (4266-66-4) + 1,8,15,22-tetraaza-cyclooctacosane-2,7,16,21-tetraone (4238-35-1)

Guidance literature:

In dichloromethane; for 2h; Ambient temperature;

DOI:10.1246/cl.1980.159

Reference yield:

1,8,15,22-tetraaza-cyclooctacosane-2,7,16,21-tetraone (4238-35-1) → 1,8,15,22-tetrabenzoyl-1,8,15,22-tetraaza-cyclooctacosane (120971-18-8)

Guidance literature:

Multi-step reaction with 2 steps

1: LiAlH₄; THF

2: THF; aqueous KOH

With tetrahydrofuran; potassium hydroxide; lithium aluminium tetrahydride;

Reference yield:

1,8,15,22-tetraaza-cyclooctacosane-2,7,16,21-tetraone (4238-35-1) → 1,8,15,22-tetrakis-(2,4-dinitro-phenyl)-1,8,15,22-tetraaza-cyclooctacosane (120233-13-8)

Guidance literature:

Multi-step reaction with 2 steps

1: LiAlH₄; THF

2: aqueous NaHCO₃; ethanol

With tetrahydrofuran; lithium aluminium tetrahydride; ethanol; sodium hydrogencarbonate;

upstream raw materials:

1,6-Hexanediamine

1,6-Bis-(2-thioxo-thiazolidin-3-yl)-hexane-1,6-dione

Downstream raw materials:

1,8,15,22-tetrabenzoyl-1,8,15,22-tetraaza-cyclooctacosane

1,8,15,22-tetrakis-(2,4-dinitro-phenyl)-1,8,15,22-tetraaza-cyclooctacosane

Refernces