4-[(E)-4-Pyridinylazo]pyridine

Base Information

• Chemical Name: 4-[(E)-4-Pyridinylazo]pyridine
• CAS No.: 4253-82-1
• Molecular Formula: C₁₀H₈N₄
• Molecular Weight: 184.2
• Mol file: 4253-82-1.mol

Synonyms:4-[(E)-4-Pyridinylazo]pyridine;

Chemical Property of 4-[(E)-4-Pyridinylazo]pyridine

Chemical Property:

• Appearance/Colour: Orange-red Solid
• Melting Point: 108-109 °C(Solv: water (7732-18-5))
• Boiling Point: 344.9±17.0 °C(Predicted)
• PKA: 2.19±0.26(Predicted)
• PSA: 50.50000
• Density: 1.18±0.1 g/cm3(Predicted)
• LogP: 2.89200
• Storage Temp.: Inert atmosphere,Room Temperature

Purity/Quality:

98%,99%, ^*data from raw suppliers

(E)-1,2-Di(pyridin-4-yl)diazene 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-[(E)-4-Pyridinylazo]pyridine

There total 12 articles about 4-[(E)-4-Pyridinylazo]pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

1,2-di(pyridin-4-yl)hydrazine (19808-51-6) → trans-4,4'-azobis(pyridine) (2632-99-7,4253-82-1,54773-17-0,127062-85-5)

Guidance literature:

With potassium tert-butylate; ammonia; at -75 - 20 ℃; for 0.05h; Sealed tube;

DOI:10.1002/anie.201610371

Reference yield: 94.0%

4-nitraminopyridine N-oxide (1124-33-0) → trans-4,4'-azobis(pyridine) (2632-99-7,4253-82-1,54773-17-0,127062-85-5)

Guidance literature:

With titanium tetrachloride; tin(ll) chloride; In tetrahydrofuran; for 0.5h; Ambient temperature;

Reference yield: 80.8%

4-nitropyridine (1122-61-8) → trans-4,4'-azobis(pyridine) (2632-99-7,4253-82-1,54773-17-0,127062-85-5)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether; for 2.5h; Heating; reactivity of nitro group at the 4 position, influence of methyl substituents positions on the reaction course; other 4-nitropyridines;

upstream raw materials:

[4,4']azoxypyridine

4-aminopyridine

4-nitropyridine

4-nitraminopyridine N-oxide

Downstream raw materials:

trans-[(4,4'-azobispyridine)(Au(C₆F₄OCH₂C₆H₄O(CH₂)11CH₃-p))2]

trans-[(4,4'-azobispyridine)(Au(C₆F₄O(CH₂)11CH₃-p))2]

Refernces

• 1、 Alfuth, Jan,Chojnacki, Jaros?aw,Po?oński, Tadeusz,Olszewska, Teresa. "Induction of chirality in 4,4′-azopyridine by halogen-bonding interaction with optically active ditopic donors". . p. 5512 - 5517. Retrieved 2019/04/04.
• 2、 Wang, Lei,Ishida, Akiko,Hashidoko, Yasuyuki,Hashimoto, Makoto. "Dehydrogenation of the NH?NH Bond Triggered by Potassium tert-Butoxide in Liquid Ammonia". . p. 870 - 873. Retrieved 2017/01/14.