Benzofuran, 2-(phenylmethyl)-

Base Information

• Chemical Name: Benzofuran, 2-(phenylmethyl)-
• CAS No.: 4265-14-9
• Molecular Formula: C15H12O
• Molecular Weight: 208.26
• Mol file: 4265-14-9.mol

Synonyms:

Chemical Property of Benzofuran, 2-(phenylmethyl)-

Chemical Property:

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Benzofuran, 2-(phenylmethyl)-

There total 48 articles about Benzofuran, 2-(phenylmethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

N’-(2-hydroxybenzylidene)-4-methylbenzene-1-sulfonohydrazide (1666-14-4) + phenylacetylene (536-74-3) → 2-benzylbenzofuran (4265-14-9)

Guidance literature:

N’-(2-hydroxybenzylidene)-4-methylbenzene-1-sulfonohydrazide; With C₃₉H₄₆BrCuN₂; caesium carbonate; for 0.0833333h; Autoclave; Sealed tube; Inert atmosphere;

phenylacetylene; In acetonitrile; at 100 ℃; for 12h; Reagent/catalyst;

DOI:10.1002/chem.202000600

Reference yield: 91.0%

salicylaldehyde (90-02-8) + phenylacetylene (536-74-3) → 2-benzylbenzofuran (4265-14-9)

Guidance literature:

salicylaldehyde; With toluene-4-sulfonic acid hydrazide; In ethanol; at 100 ℃; for 1h;

phenylacetylene; With Tridecane; caesium carbonate; In ethanol; at 100 ℃; for 5h; Solvent; Reagent/catalyst; Temperature;

DOI:10.1002/ejoc.201600671

Reference yield: 90.0%

2-benzoylbenzofuran (6272-40-8) → 2-benzylbenzofuran (4265-14-9)

Guidance literature:

With potassium hydroxide; hydrazine hydrate; In water; diethylene glycol;

upstream raw materials:

2-benzoylbenzofuran

2-(2-methoxy-phenyl)-4-phenyl-acetoacetonitrile

iodobenzene

3-(2-hydroxyphenyl)propyne

Downstream raw materials:

2-benzyldihydrobenzofuran

(benzofuran-2-yl)phenylmethanol

2-benzoylbenzofuran

2-(methoxy(phenyl)methyl)benzofuran