1,2-Cyclooctanediol

Base Information

• Chemical Name: 1,2-Cyclooctanediol
• CAS No.: 4277-32-1
• Molecular Formula: C8H16O2
• Molecular Weight: 144.214
• European Community (EC) Number: 255-885-8
• DSSTox Substance ID: DTXSID90962562
• Nikkaji Number: J80.787G
• Wikidata: Q82944273
• Mol file: 4277-32-1.mol

Synonyms:1,2-Cyclooctanediol;cyclooctane-1,2-diol;42565-22-0;trans-Cyclooctane-1,2-diol;EINECS 255-885-8;4277-32-1;TRANS-1,2-CYCLOOCTANEDIOL;SCHEMBL371487;DTXSID90962562;AKOS006228855;FT-0605178;FT-0690237

Chemical Property of 1,2-Cyclooctanediol

Chemical Property:

• Boiling Point: 160-172 °C(Press: 1.5 Torr)
• PKA: 14.52±0.40(Predicted)
• PSA: 40.46000
• Density: 1.061±0.06 g/cm3(Predicted)
• LogP: 1.06240
• XLogP3: 1.3
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 144.115029749
• Heavy Atom Count: 10
• Complexity: 81.3

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1CCCC(C(CC1)O)O

Technology Process of 1,2-Cyclooctanediol

There total 44 articles about 1,2-Cyclooctanediol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.8%

cis-Cyclooctene (931-88-4,931-87-3,25267-51-0) → Cyclooctene oxide (286-62-4) + 1,2-cyclooctanediol (4277-32-1)

Guidance literature:

With tert.-butylhydroperoxide; air; C₂₂H₃₈ClMoNO₅Si; at 55 ℃; under 760.051 Torr; Further Variations:; Catalysts; Solvents; Product distribution;

DOI:10.1039/b102523f

Reference yield: 92.0%

1,2-cyclooctene (931-88-4,22770-27-0,3958-30-3,25267-51-0) → Cyclooctene oxide (286-62-4) + 1,2-cyclooctanediol (4277-32-1)

Guidance literature:

With dihydrogen peroxide; In water; at 85 ℃; Green chemistry;

DOI:10.1039/c6ta02566h

Reference yield: 71.0%

cis-Cyclooctene (931-88-4,931-87-3,25267-51-0) → Cyclooctene oxide (286-62-4) + 1,2-cyclooctanediol (4277-32-1) + 5-chloro-1-cyclooctene (1855-55-6) + 3-chlorocyclooct-1-ene (14796-70-4)

Guidance literature:

With water; dihydrogen peroxide; gallium(III) trichloride; In iso-butanol; at 80 ℃; for 4h; Further byproducts.;

DOI:10.1002/chem.200700074

upstream raw materials:

cis-Cyclooctene

1,2-cyclooctene

Cyclooctan

tert.-butylhydroperoxide

Downstream raw materials:

octane-1,8-dioic acid

cyclooctane-1,2-dione

2-hydroxycyclooctyl p-toluenesulfonate

1,8-octanedial

Refernces

• 1、 Maurya, Abhishek,Haldar, Chanchal. "Liquid-phase oxidation of olefins with rare hydronium ion salt of dinuclear dioxido-vanadium(V) complexes and comparative catalytic studies with analogous copper complexes". . . Retrieved 2021/02/26.
• 2、 Chowdhury, Habibar,Bera, Rajesh,Rizzoli, Corrado,Adhikary, Chandan. "Double end-on azido derivative of a tridentate (NNO) Schiff base dimeric copper(II) complex: synthesis, X-ray structure, magnetic property and catalytic effectiveness". . p. 3062 - 3078. Retrieved 2020/10/29.