4-Thiazolecarboxamide, 2-[3-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-1-azetidinyl]-N-[(1S)-1-[[[(1,1- dimethylethyl)diphenylsilyl]oxy]methyl]-3-methylbutyl]-

Base Information

Chemical Name:4-Thiazolecarboxamide, 2-[3-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-1-azetidinyl]-N-[(1S)-1-[[[(1,1- dimethylethyl)diphenylsilyl]oxy]methyl]-3-methylbutyl]-
CAS No.:429669-80-7
Molecular Formula:C45H57N3O3SSi2
Molecular Weight:776.203
Hs Code.:
Mol file:429669-80-7.mol

4-Thiazolecarboxamide,
2-[3-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-1-azetidinyl]-N-[(1S)-1-[[[(1,1-
dimethylethyl)diphenylsilyl]oxy]methyl]-3-methylbutyl]-

Synonyms:

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Chemical Property of 4-Thiazolecarboxamide, 2-[3-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-1-azetidinyl]-N-[(1S)-1-[[[(1,1- dimethylethyl)diphenylsilyl]oxy]methyl]-3-methylbutyl]-

Chemical Property:

Purity/Quality:

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Technology Process of 4-Thiazolecarboxamide, 2-[3-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-1-azetidinyl]-N-[(1S)-1-[[[(1,1- dimethylethyl)diphenylsilyl]oxy]methyl]-3-methylbutyl]-

There total 3 articles about 4-Thiazolecarboxamide, 2-[3-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-1-azetidinyl]-N-[(1S)-1-[[[(1,1- dimethylethyl)diphenylsilyl]oxy]methyl]-3-methylbutyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 429666-50-2
3-t-butyldiphenylsilyloxy-1-(4-ethoxycarbonyl-1,3-thiazol-2-yl)azetidine

: [(1S)-1-(t-butyldiphenylsilyloxymethyl)-3-methylbutyl]carbamic acid benzyl ester

: (1S)-1-(t-butyldiphenylsilyloxymethyl)-3-methylbutylamine-trimethylaluminium

: 429669-80-7
3-t-butyldiphenylsilyloxy-1-{4-[(1S)-1-(t-butyldiphenylsilyloxymethyl)-3-methylbutylcarbamoyl]-1,3-thiazol-2-yl}azetidine

Guidance literature:: With acetic acid; In methanol; palladium on charcoal; ethyl acetate; benzene;

Reference yield:

: 429666-44-4
1-(4-ethoxycarbonyl-1,3-thiazol-2-yl)-3-hydroxyazetidine

: 429669-80-7
3-t-butyldiphenylsilyloxy-1-{4-[(1S)-1-(t-butyldiphenylsilyloxymethyl)-3-methylbutylcarbamoyl]-1,3-thiazol-2-yl}azetidine

Guidance literature:: Multi-step reaction with 2 steps

1: N-methyl-acetamide; ethanol

2: acetic acid / methanol; palladium on charcoal; ethyl acetate; benzene

With acetic acid; In N-methyl-acetamide; methanol; palladium on charcoal; ethanol; ethyl acetate; benzene;

Reference yield:

: 58479-61-1
tert-butylchlorodiphenylsilane

: 429669-80-7
3-t-butyldiphenylsilyloxy-1-{4-[(1S)-1-(t-butyldiphenylsilyloxymethyl)-3-methylbutylcarbamoyl]-1,3-thiazol-2-yl}azetidine

Guidance literature:: Multi-step reaction with 2 steps

1: N-methyl-acetamide; ethanol

2: acetic acid / methanol; palladium on charcoal; ethyl acetate; benzene

With acetic acid; In N-methyl-acetamide; methanol; palladium on charcoal; ethanol; ethyl acetate; benzene;