2-Propyn-1-ol, 3-(dimethylphenylsilyl)-

Base Information

Chemical Name:2-Propyn-1-ol, 3-(dimethylphenylsilyl)-
CAS No.:43019-63-2
Molecular Formula:C11H14OSi
Molecular Weight:190.317
Hs Code.:
DSSTox Substance ID:DTXSID20437470
Nikkaji Number:J1.859.129D
Wikidata:Q82252965

Synonyms:43019-63-2;2-Propyn-1-ol, 3-(dimethylphenylsilyl)-;3-(Phenyldimethylsilyl)-2-propyne-1-ol;CTK1D2857;3-[DIMETHYL(PHENYL)SILYL]PROP-2-YN-1-OL;DTXSID20437470

Suppliers and Price of 2-Propyn-1-ol, 3-(dimethylphenylsilyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 2-Propyn-1-ol, 3-(dimethylphenylsilyl)-

Chemical Property:

PSA：20.23000
LogP:1.13690
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:190.081391600
Heavy Atom Count:13
Complexity:215

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C[Si](C)(C#CCO)C1=CC=CC=C1

Technology Process of 2-Propyn-1-ol, 3-(dimethylphenylsilyl)-

There total 9 articles about 2-Propyn-1-ol, 3-(dimethylphenylsilyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 107-19-7
propargyl alcohol

: 768-33-2
phenyldimethylsilyl chloride

: 43019-63-2
3-(phenyldimethylsilyl)prop-2-yn-1-ol

Guidance literature:: propargyl alcohol; With n-butyllithium; In tetrahydrofuran; hexane; at -78 - 22 ℃;

phenyldimethylsilyl chloride; In tetrahydrofuran; hexane; at -78 - 22 ℃; for 12h; Further stages.;
DOI:10.1002/anie.200700841

Reference yield: 85.0%

: 862735-92-0
dimethyl(phenyl)(3-((tetrahydro-2H-pyran-2-yl)oxy)prop-1-yn-1-yl)silane

: 43019-63-2
3-(phenyldimethylsilyl)prop-2-yn-1-ol

Guidance literature:: With toluene-4-sulfonic acid; In methanol; Inert atmosphere; Reflux;
DOI:10.1002/chem.201501648

Reference yield:

: 6089-04-9
3-(tetrahydropyran-2'-yloxy)propyne

: 768-33-2
phenyldimethylsilyl chloride

: 43019-63-2
3-(phenyldimethylsilyl)prop-2-yn-1-ol

Guidance literature:: 3-(tetrahydropyran-2'-yloxy)propyne; With n-butyllithium; In tetrahydrofuran; at -78 ℃; for 1.5h; Inert atmosphere;

phenyldimethylsilyl chloride; In tetrahydrofuran; at -78 - 20 ℃; for 3.5h; Inert atmosphere;

With toluene-4-sulfonic acid; In methanol; at 20 ℃; for 2h; Inert atmosphere;
DOI:10.1016/j.tet.2018.04.021