2-(Benzyl(1-(4-methoxyphenyl)propan-2-yl)amino)-1-(4-(benzyloxy)-3-nitrophenyl)ethanone

Base Information

• Chemical Name: 2-(Benzyl(1-(4-methoxyphenyl)propan-2-yl)amino)-1-(4-(benzyloxy)-3-nitrophenyl)ethanone
• CAS No.: 43229-66-9
• Molecular Formula: C32H32N2O5
• Molecular Weight: 524.616
• European Community (EC) Number: 610-116-9
• UNII: TF42UG4W3R
• DSSTox Substance ID: DTXSID50705457
• Nikkaji Number: J1.630.833A
• Mol file: 43229-66-9.mol

Synonyms:43229-66-9;2-(Benzyl(1-(4-methoxyphenyl)propan-2-yl)amino)-1-(4-(benzyloxy)-3-nitrophenyl)ethanone;2-[benzyl-[1-(4-methoxyphenyl)propan-2-yl]amino]-1-(3-nitro-4-phenylmethoxyphenyl)ethanone;Ethanone, 2-[[2-(4-methoxyphenyl)-1-methylethyl](phenylmethyl)amino]-1-[3-nitro-4-(phenylmethoxy)phenyl]-;TF42UG4W3R;SCHEMBL1134256;AMY7245;DTXSID50705457;GYWPAIAUFMGISM-UHFFFAOYSA-N;alpha-[Benzyl(alpha-methyl-4-methoxyphenethyl)amino]-4'-(benzyloxy)-3'-nitroacetophenone;2-[[2-(4-Methoxyphenyl)-1-methylethyl](phenylmethyl)amino]-1-[3-nitro-4-(phenylmethoxy)phenyl]ethanone;2-{Benzyl[1-(4-methoxyphenyl)propan-2-yl]amino}-1-[4-(benzyloxy)-3-nitrophenyl]ethan-1-one;ethanone,2-((2-(4-methoxyphenyl)-1-methylethyl)(phenylmethyl)amino)-1-[3-nitro-4-(phenylmethoxy)phenyl]-

Chemical Property of 2-(Benzyl(1-(4-methoxyphenyl)propan-2-yl)amino)-1-(4-(benzyloxy)-3-nitrophenyl)ethanone

Chemical Property:

• Vapor Pressure: 6.59E-18mmHg at 25°C
• Melting Point: 98-100°C
• Boiling Point: 671.8oC at 760 mmHg
• PKA: 5.43±0.50(Predicted)
• Flash Point: 360.1oC
• PSA: 84.59000
• Density: 1.201g/cm3
• LogP: 7.02170
• Storage Temp.: -20°C Freezer, Under inert atmosphere
• Solubility.: Chloroform (Slightly), Methanol (Slightly)
• XLogP3: 6.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 12
• Exact Mass: 524.23112213
• Heavy Atom Count: 39
• Complexity: 737

Purity/Quality:

99.9% ^*data from raw suppliers

2-(Benzyl(1-(4-methoxyphenyl)propan-2-yl)amino)-1-(4-(benzyloxy)-3-nitrophenyl)ethanone ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC(CC1=CC=C(C=C1)OC)N(CC2=CC=CC=C2)CC(=O)C3=CC(=C(C=C3)OCC4=CC=CC=C4)[N+](=O)[O-]
• Uses: 2-(Benzyl(1-(4-methoxyphenyl)propan-2-yl)amino)-1-(4-(benzyloxy)-3-nitrophenyl)ethanone is used in the preparation of 3-acylamino-4-hydroxy-α-(N-substituted aminomethyl)benzyl alcohol derivatives as β-adrenoreceptor stimulants.

Technology Process of 2-(Benzyl(1-(4-methoxyphenyl)propan-2-yl)amino)-1-(4-(benzyloxy)-3-nitrophenyl)ethanone

There total 1 articles about 2-(Benzyl(1-(4-methoxyphenyl)propan-2-yl)amino)-1-(4-(benzyloxy)-3-nitrophenyl)ethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 1-(4-benzyloxy-3-nitrophenyl)-2-{benzyl-[2-(4-methoxyphenyl)-1-methylethyl]amino}ethanone (43229-66-9)

Guidance literature:

entspr. Bromacetophenon, entspr. Amin;

Reference yield:

1-(4-benzyloxy-3-nitrophenyl)-2-{benzyl-[2-(4-methoxyphenyl)-1-methylethyl]amino}ethanone (43229-66-9) → 1-(4-benzyloxy-3-nitrobenzene)-2-{benzyl-[2-(4-methoxyphenyl)-1-methylethyl]amino}ethanol + 1-(4-benzyloxy-3-nitrobenzene)-2-{benzyl-[2-(4-methoxyphenyl)-1-methylethyl]amino}ethanol

Guidance literature:

With sodium tetrahydroborate; In methanol; at 25 - 30 ℃;

Reference yield:

1-(4-benzyloxy-3-nitrophenyl)-2-{benzyl-[2-(4-methoxyphenyl)-1-methylethyl]amino}ethanone (43229-66-9) → 2-[N-benzyl-N-[1-methyl-2-(4-methoxy-3-methylphenyl)]ethyl]amino-1-(4-benzyloxy-3-nitrophenyl)ethanol

Guidance literature:

Multi-step reaction with 2 steps

1: hydrogenchloride; zinc(II) chloride; acetic acid / water / 1 h / 80 °C

2: sodium tetrahydroborate / dimethyl sulfoxide / 1 h / 25 °C

With hydrogenchloride; sodium tetrahydroborate; acetic acid; zinc(II) chloride; In water; dimethyl sulfoxide;

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 43229-66-9 Ethanone, 2-[[2-(4-Methoxyphenyl)-1-Methylethyl](phenylMethyl)aMino]-1-[3-nitro-4-(phenylMethoxy)phenyl]-

Send

Send

Metric Ton KG G Pound L ML

Send

Send