5-Methoxy-2-(4-methoxybenzyl)phenol

Base Information

• Chemical Name: 5-Methoxy-2-(4-methoxybenzyl)phenol
• CAS No.: 433331-88-5
• Molecular Formula: C15H16O3
• Molecular Weight: 244.29
• DSSTox Substance ID: DTXSID40463433
• Nikkaji Number: J3.139.268C
• Wikidata: Q82288308
• Mol file: 433331-88-5.mol

Synonyms:5-methoxy-2-(4-methoxybenzyl)phenol;433331-88-5;SCHEMBL227700;DTXSID40463433;WAXQLKGYUGFJTL-UHFFFAOYSA-N

Chemical Property of 5-Methoxy-2-(4-methoxybenzyl)phenol

Chemical Property:

• XLogP3: 3.4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 244.109944368
• Heavy Atom Count: 18
• Complexity: 236

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: COC1=CC=C(C=C1)CC2=C(C=C(C=C2)OC)O

Technology Process of 5-Methoxy-2-(4-methoxybenzyl)phenol

There total 6 articles about 5-Methoxy-2-(4-methoxybenzyl)phenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

O-methylresorcine (150-19-6) + p-methoxybenzyl chloride (824-94-2) → 1-((3-methoxyphenoxy)methyl)-4-methoxybenzene (1160046-95-6) + 5-methoxy-2-(4-methoxybenzyl)phenol (433331-88-5)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; for 0.25h; sonication;

DOI:10.1021/jo800577f

Reference yield: 70.0%

1-((3-methoxyphenoxy)methyl)-4-methoxybenzene (1160046-95-6) → 5-methoxy-2-(4-methoxybenzyl)phenol (433331-88-5)

Guidance literature:

With boron trifluoride diethyl etherate; In dichloromethane; at 0 - 20 ℃; regioselective reaction; Inert atmosphere;

DOI:10.1016/j.tetlet.2012.10.058

Reference yield: 40.0%

1-((3-methoxyphenoxy)methyl)-4-methoxybenzene (1160046-95-6) → 2,6-bis-(4-methoxybenzyl)-3-methoxyphenol (1160046-98-9) + 5-methoxy-2-(4-methoxybenzyl)phenol (433331-88-5)

Guidance literature:

With camphor-10-sulfonic acid; In fluorobenzene; at 60 ℃; for 17h; Inert atmosphere;

DOI:10.1021/jo9007833

upstream raw materials:

2-hydroxy-4,4'-dimethoxydiphenylmethanol

O-methylresorcine

p-methoxybenzyl chloride

1-((3-methoxyphenoxy)methyl)-4-methoxybenzene

Downstream raw materials:

4-[5-methoxy-2-(4-methoxybenzyl)phenoxy]phenol

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 433331-88-5 Phenol, 5-methoxy-2-[(4-methoxyphenyl)methyl]-

Send

Send

Metric Ton KG G Pound L ML

Send

Send