4-[1,1,2,2-Tetrafluoro-2-(4-hydroxyphenyl)ethyl]phenol

Base Information

Chemical Name:4-[1,1,2,2-Tetrafluoro-2-(4-hydroxyphenyl)ethyl]phenol
CAS No.:433719-69-8
Molecular Formula:C14H10F4O2
Molecular Weight:286.226
Hs Code.:2908199090
DSSTox Substance ID:DTXSID10463849
Wikidata:Q82288915
Mol file:433719-69-8.mol

Synonyms:433719-69-8;4-[1,1,2,2-tetrafluoro-2-(4-hydroxyphenyl)ethyl]phenol;1,2-Bis(4-hydroxyphenyl)-1,1,2,2-tetrafluoroethane;Phenol, 4,4'-(tetrafluoro-1,2-ethanediyl)bis-;SCHEMBL2868121;DTXSID10463849;YFWMKHJNNZCGHF-UHFFFAOYSA-N;MFCD03412179;4,4'-(perfluoroethane-1,2-diyl)diphenol;1,2-Bis(4-hydroxyphenyl)-1,1,2,2-tetrafluoroethane 99%

Suppliers and Price of 4-[1,1,2,2-Tetrafluoro-2-(4-hydroxyphenyl)ethyl]phenol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of 4-[1,1,2,2-Tetrafluoro-2-(4-hydroxyphenyl)ethyl]phenol

Chemical Property:

Boiling Point:379.1±42.0 °C(Predicted)
PSA：40.46000
Density:1.407±0.06 g/cm3(Predicted)
LogP:3.98160
XLogP3:3.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:3
Exact Mass:286.06169221
Heavy Atom Count:20
Complexity:287

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1C(C(C2=CC=C(C=C2)O)(F)F)(F)F)O

Technology Process of 4-[1,1,2,2-Tetrafluoro-2-(4-hydroxyphenyl)ethyl]phenol

There total 1 articles about 4-[1,1,2,2-Tetrafluoro-2-(4-hydroxyphenyl)ethyl]phenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 477529-31-0
1,2-di(4-benzyloxyphenyl)tetrafluoroethane

: 433719-69-8
1,2-bis(4-hydroxyphenyl)tetrafluoroethane

Guidance literature:: With hydrogen; palladium on activated carbon; In ethanol;

Reference yield: 76.0%

: 433719-69-8
1,2-bis(4-hydroxyphenyl)tetrafluoroethane

: 433719-70-1
C₁₄H₂₂F₄O₂

Guidance literature:: With hydrogen; Rh on carbon; In isopropyl alcohol; at 60 ℃; under 3750.3 Torr;
DOI:10.1016/S0022-1139(01)00488-2

Reference yield:

: 433719-69-8
1,2-bis(4-hydroxyphenyl)tetrafluoroethane

: 433719-72-3
4-[2-(3,3-dimethyl-1,5-dioxa-spiro[5.5]undec-9-yl)-1,1,2,2-tetrafluoro-ethyl]-cyclohexanone

Guidance literature:: Multi-step reaction with 3 steps

1: 76 percent / H₂ / 5 percent Rh/C / propan-2-ol / 60 °C / 3750.3 Torr

2: 79 percent / PCC / CH₂Cl₂ / 18 h / 20 °C

3: 83 percent / H₂SO₄ / cyclohexane / 10 h / Heating

With sulfuric acid; hydrogen; pyridinium chlorochromate; Rh on carbon; In dichloromethane; cyclohexane; isopropyl alcohol;
DOI:10.1016/S0022-1139(01)00488-2