3-(2-Chlorophenyl)pyridine

Base Information

Chemical Name:3-(2-Chlorophenyl)pyridine
CAS No.:4381-37-7
Molecular Formula:C11H8ClN
Molecular Weight:189.644
Hs Code.:
DSSTox Substance ID:DTXSID60450840
Mol file:4381-37-7.mol

Synonyms:3-(2-chlorophenyl)pyridine;4381-37-7;3-(2-chloro-phenyl)pyridine;3-(2-chlorophenyl)-pyridine;SCHEMBL551165;pyridine,3-(2-chlorophenyl)-;DTXSID60450840;GYSYWLZDSFTCEP-UHFFFAOYSA-N;FT-0703843

Suppliers and Price of 3-(2-Chlorophenyl)pyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 3-(2-Chlorophenyl)pyridine

Chemical Property:

XLogP3:3.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:189.0345270
Heavy Atom Count:13
Complexity:160

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C(=C1)C2=CN=CC=C2)Cl

Technology Process of 3-(2-Chlorophenyl)pyridine

There total 7 articles about 3-(2-Chlorophenyl)pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 1379538-69-8
N-allyl-N-tert-butoxycarbonyl-(2-chlorophenyl)ethynylamine

: 4381-37-7
3-(o-chlorophenyl)pyridine

Guidance literature:: N-allyl-N-tert-butoxycarbonyl-(2-chlorophenyl)ethynylamine; With N,N,N,N,-tetramethylethylenediamine; sec.-butyllithium; In tetrahydrofuran; cyclohexane; at -78 ℃; for 1h; Inert atmosphere;

With o-tetrachloroquinone; acetic acid; In tetrahydrofuran; cyclohexane; at -78 - 20 ℃; chemoselective reaction; Inert atmosphere;
DOI:10.1021/ja303002a

Reference yield: 50.0%

: 4381-37-7
3-(o-chlorophenyl)pyridine

Guidance literature:

Reference yield: 43.0%

: 626-55-1,163928-56-1
3-Bromopyridine

: 615-41-8
2-iodochlorobenzene

: 4381-37-7
3-(o-chlorophenyl)pyridine

Guidance literature:: 3-Bromopyridine; With n-butyllithium; In diethyl ether; hexane; at -90 ℃; for 0.5h;

With tributyltin chloride; In diethyl ether; hexane; at -70 ℃; for 4h;

2-iodochlorobenzene; With palladium diacetate; triphenylphosphine; In N,N-dimethyl-formamide; at 120 ℃; for 144h;
DOI:10.1002/1099-0690(200208)2002:15<2547::AID-EJOC2547>3.0.CO;2-A