6-Oxo-1-(beta-D-ribofuranosyl)nicotinic acid

Base Information

Chemical Name:6-Oxo-1-(beta-D-ribofuranosyl)nicotinic acid
CAS No.:66171-44-6
Molecular Formula:C11H13NO7
Molecular Weight:271.2234
Hs Code.:
DSSTox Substance ID:DTXSID80984657
Wikidata:Q82971943
ChEMBL ID:CHEMBL3249605

Synonyms:6-oxo-1-(beta-D-ribofuranosyl)nicotinic acid

Suppliers and Price of 6-Oxo-1-(beta-D-ribofuranosyl)nicotinic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 6-Oxo-1-(beta-D-ribofuranosyl)nicotinic acid

Chemical Property:

Vapor Pressure:1.33E-17mmHg at 25°C
Boiling Point:613.3°C at 760 mmHg
Flash Point:324.7°C
Density:1.729g/cm³
XLogP3:-1.9
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:3
Exact Mass:271.06920175
Heavy Atom Count:19
Complexity:458

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=O)N(C=C1C(=O)O)C2C(C(C(O2)CO)O)O
Isomeric SMILES:C1=CC(=O)N(C=C1C(=O)O)[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O

Technology Process of 6-Oxo-1-(beta-D-ribofuranosyl)nicotinic acid

There total 4 articles about 6-Oxo-1-(beta-D-ribofuranosyl)nicotinic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 96639-59-7
1,6-Dihydro-6-oxo-1-(2',3',5'-tri-O-acetyl-β-D-ribofuranosyl)-3-pyridincarbonsaeure

: 66171-44-6
1,6-Dihydro-6-oxo-1-(β-D-ribofuranosyl)-3-pyridincarbonsaeure

Guidance literature:: With ammonium hydroxide; In methanol; for 4h; Ambient temperature;

Reference yield:

: 5006-66-6
6-hydroxynicotinic acid

: 66171-44-6
1,6-Dihydro-6-oxo-1-(β-D-ribofuranosyl)-3-pyridincarbonsaeure

Guidance literature:: Multi-step reaction with 3 steps

1: acetonitrile / 4 h / Ambient temperature

2: 88 percent / SnCl₄ / acetonitrile / 20 h / Ambient temperature

3: 72 percent / 33 percent aqu. NH₃ / methanol / 4 h / Ambient temperature

With ammonium hydroxide; tin(IV) chloride; In methanol; acetonitrile;

Reference yield:

: 36972-82-4
6-(Trimethylsilyloxy)-3-pyridincarbonsaeure-(trimethylsilyl)ester

: 66171-44-6
1,6-Dihydro-6-oxo-1-(β-D-ribofuranosyl)-3-pyridincarbonsaeure

Guidance literature:: Multi-step reaction with 2 steps

1: 88 percent / SnCl₄ / acetonitrile / 20 h / Ambient temperature

2: 72 percent / 33 percent aqu. NH₃ / methanol / 4 h / Ambient temperature

With ammonium hydroxide; tin(IV) chloride; In methanol; acetonitrile;