9-(Cyanomethylene)fluorene

Base Information

• Chemical Name: 9-(Cyanomethylene)fluorene
• CAS No.: 4425-74-5
• Molecular Formula: C15H9N
• Molecular Weight: 203.243
• Hs Code.: 2926909090
• DSSTox Substance ID: DTXSID401289621
• Nikkaji Number: J963.549A
• Mol file: 4425-74-5.mol

Synonyms:2-(9h-fluoren-9-ylidene)acetonitrile;4425-74-5;9-(Cyanomethylene)fluorene;(9-fluorenylidene)acetonitrile;fluoren-9-ylidene-acetonitrile;SCHEMBL2435383;DTXSID401289621;9H-Fluoren-9-ylideneacetonitrile #

Chemical Property of 9-(Cyanomethylene)fluorene

Chemical Property:

• PSA: 23.79000
• LogP: 3.62228
• XLogP3: 3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 203.073499291
• Heavy Atom Count: 16
• Complexity: 322

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CC=C2C(=C1)C3=CC=CC=C3C2=CC#N

Technology Process of 9-(Cyanomethylene)fluorene

There total 2 articles about 9-(Cyanomethylene)fluorene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 41.0%

C16H9N2(1-)*C13H13N2O(1+) → 9-Benzylidene-9H-fluorene (1836-87-9) + 2-(9H-fluoren-9-ylidene)acetonitrile (4425-74-5)

Guidance literature:

In acetonitrile; at 60 ℃; for 60h;

DOI:10.1021/jo971969h

Reference yield: 8.0%

9-fluorenone (486-25-9,952573-42-1) + acetonitrile (75-05-8,26809-02-9) → 2-(9H-fluoren-9-ylidene)acetonitrile (4425-74-5) + 2-(9-hydroxy-9H-fluoren-9-yl)acetonitrile (17190-25-9)

Guidance literature:

electrochemical reduction;

Reference yield: 92.0%

2-(9H-fluoren-9-ylidene)acetonitrile (4425-74-5) + N-benzyl-N-(methoxymethyl)-N-[(trimethylsilyl)methyl]amine (93102-05-7) → 1'-benzylspiro[fluorene-9,3'-pyrrolidine]-4'-carbonitrile

Guidance literature:

With lithium fluoride; In N,N-dimethyl-formamide; for 5h; Solvent; Reflux; Inert atmosphere; Schlenk technique;

DOI:10.1007/s10593-019-02516-3

upstream raw materials:

9-fluorenone

acetonitrile

Downstream raw materials:

9-fluorenone