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UNC3866

Base Information
UNC3866

Synonyms:UNC3866;N-[4-(1,1-Dimethylethyl)benzoyl]-L-phenylalanyl-L-alanyl-L-leucyl-N6,N6-diethyl-L-lysyl-L-serine methyl ester;CS-2491;UNC 3866;UNC-3866;(3S,6S,9S,12S,15S)-Methyl 3-benzyl-1-(4-(tert-butyl)phenyl)-12-(4-(diethylamino)butyl)-15-(hydroxymethyl)-9-isobutyl-6-methyl-1,4,7,10,13-pentaoxo-2,5,8,11,14-pentaazahexadecan-16-oate;L-Serine, N-[4-(1,1-dimethylethyl)benzoyl]-L-phenylalanyl-L-alanyl-L-leucyl-N6,N6-diethyl-L-lysyl-, methyl ester;UNC3866,inhibit,Histone Methyltransferase,UNC-3866,Inhibitor,UNC 3866;UNC3866, 10 mM in DMSO

Suppliers and Price of UNC3866
Supply Marketing:
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • TRC
  • N-?[4-?(1,?1-Dimethylethyl)?benzoyl]?-?L-?phenylalanyl-?L-?alanyl-?L-?leucyl-?N6,?N6-?diethyl-?L-?lysyl-?L-serineMethylEster
  • 5mg
  • $ 420.00
  • DC Chemicals
  • UNC3866 >95%
  • 100 mg
  • $ 750.00
  • ChemScene
  • UNC3866 >98.0%
  • 50mg
  • $ 912.00
  • ChemScene
  • UNC3866 >98.0%
  • 5mg
  • $ 144.00
  • ChemScene
  • UNC3866 >98.0%
  • 10mg
  • $ 252.00
  • ChemScene
  • UNC3866 >98.0%
  • 100mg
  • $ 1620.00
  • ChemScene
  • UNC3866 >98.0%
  • 25mg
  • $ 492.00
  • Cayman Chemical
  • UNC3866 ≥95%
  • 25mg
  • $ 475.00
  • Cayman Chemical
  • UNC3866 ≥95%
  • 10mg
  • $ 228.00
  • Cayman Chemical
  • UNC3866 ≥95%
  • 5mg
  • $ 124.00
Total 9 raw suppliers
Chemical Property of UNC3866
Chemical Property:
  • Melting Point:1034.5±65.0 °C(Predicted) 
  • PKA:13.39±0.46(Predicted) 
  • Storage Temp.:Sealed in dry,Store in freezer, under -20°C 
  • Solubility.:Soluble in DMSO 
Purity/Quality:

99%, *data from raw suppliers

N-?[4-?(1,?1-Dimethylethyl)?benzoyl]?-?L-?phenylalanyl-?L-?alanyl-?L-?leucyl-?N6,?N6-?diethyl-?L-?lysyl-?L-serineMethylEster *data from reagent suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes: 
MSDS Files:
Useful:
  • Description UNC3866 is an inhibitor of chromobox homolog 7 (CBX7; Kd = 97 nM). It also binds to CBX4 (Kd = 94 nM) but is greater than 6-fold selective over CBX2, 6, and 8 and the chromodomain Y family (CDY) chromodomains CDY1, L1b, and L2 (Kds = 0.61-6.3 μM). UNC3866 pretreatment (30 μM) of PC3 lysates completely inhibits chemiprecipitation of CBX7. It induces a senescent-like morphology and reduces growth of PC3 cells with an EC50 value of 7.6 μM.
  • Uses Polycomb group proteins (CBX4, CBX7) regulate cell fate decisions during embryogenesis. N-?[4-?(1,?1-Dimethylethyl)?benzoyl]?-?L-?phenylalanyl-?L-?alanyl-?L-?leucyl-?N6,?N6-?diethyl-?L-?lysyl-?L-serine Methyl Ester is a selective antagonist of CBX4 and CBX7 chromodomains. It also inhibits prostate cell proliferation.
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