1,5-DiMethyl-4-hexenyl 4-Methylbenzenesulfonate1,5-DiMethyl-4-hexenyl 4-Methylbenzenesulfonate

Base Information

• Chemical Name: 1,5-DiMethyl-4-hexenyl 4-Methylbenzenesulfonate1,5-DiMethyl-4-hexenyl 4-Methylbenzenesulfonate
• CAS No.: 4582-61-0
• Molecular Formula: C₁₅H₂₂O₃S
• Molecular Weight: 282.404
• Mol file: 4582-61-0.mol

Synonyms:6-Methyl-2-[p-toluolsulfonyloxy]-hept-5-en;tosylate de methyl-2-ol-6-heptene-2;1,5-dimethylhex-4-enyl 4-methylbenzenesulfonate;6-Methyl-2-(p-toluolsulfonyloxy)-hept-5-en;1,5-Dimethyl-4-hexenyl 4-methylbenzenesulfonate1,5-Dimethyl-4-hexenyl 4-methylbenzenesulfonate;6-Methyl-5-hepten-2-p-toluolsulfonat;

Chemical Property of 1,5-DiMethyl-4-hexenyl 4-Methylbenzenesulfonate1,5-DiMethyl-4-hexenyl 4-Methylbenzenesulfonate

Chemical Property:

• PSA: 51.75000
• LogP: 4.91600
• Solubility.: Chloroform

Purity/Quality:

1,5-Dimethyl-4-hexenyl4-methylbenzenesulfonate1,5-Dimethyl-4-hexenyl4-methylbenzenesulfonate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 1,5-Dimethyl-4-hexenyl 4-methylbenzenesulfonate1,5-Dimethyl-4-hexenyl 4-methylbenzenesulfonate is an protected intermediate in the synthesis of Isometheptene (I821325), a sympathomimetic amine that shows some antihypertensive activity.

Technology Process of 1,5-DiMethyl-4-hexenyl 4-Methylbenzenesulfonate1,5-DiMethyl-4-hexenyl 4-Methylbenzenesulfonate

There total 3 articles about 1,5-DiMethyl-4-hexenyl 4-Methylbenzenesulfonate1,5-DiMethyl-4-hexenyl 4-Methylbenzenesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

6-Methyl-hept-5-en-2-on (110-93-0,129085-68-3) → 2-<(tolylsulfonyl)oxy>-6-methyl-5-heptene (4582-61-0)

Guidance literature:

Multi-step reaction with 2 steps

1: LiAlH₄ / diethyl ether

2: Py

With pyridine; lithium aluminium tetrahydride; In diethyl ether;

DOI:10.1021/jo00404a025

Reference yield:

6-methylhept-5-en-2-ol (4630-06-2,1569-60-4) + p-toluenesulfonyl chloride (98-59-9) → 2-<(tolylsulfonyl)oxy>-6-methyl-5-heptene (4582-61-0)

Guidance literature:

With pyridine;

DOI:10.1021/jo00404a025

Reference yield:

→ 2-<(tolylsulfonyl)oxy>-6-methyl-5-heptene (4582-61-0)

Guidance literature:

6-Methyl-hept-5-en-2-ol, p-Toluolsulfonylchlorid in Py.;

upstream raw materials:

6-methylhept-5-en-2-ol

p-toluenesulfonyl chloride

6-Methyl-hept-5-en-2-on

Downstream raw materials:

1-Benzenesulfonyl-4-[2-(1,5-dimethyl-hex-4-enyloxy)-ethoxy]-benzene

8-Benzenesulfonyl-8-(1,5-dimethyl-hex-4-enyl)-1,4-dioxa-spiro[4.5]dec-6-ene

cis-4-(6-methyl-5-hepten-2-yl)-1-methyl-2-cyclohexen-1-ol

zingiberenol