6-methoxy-2-methyl-N-[(E)-pyridin-3-ylmethylideneamino]quinolin-4-amine

Base Information

Chemical Name:6-methoxy-2-methyl-N-[(E)-pyridin-3-ylmethylideneamino]quinolin-4-amine
CAS No.:29125-41-5
Molecular Formula:C₁₇H₁₆N₄O
Molecular Weight:292.34
Hs Code.:
ChEMBL ID:CHEMBL4514167
NSC Number:300601
Mol file:29125-41-5.mol

Synonyms:CHEMBL4514167;29125-41-5;NSC300601;BDBM50515994;NSC-300601

Suppliers and Price of 6-methoxy-2-methyl-N-[(E)-pyridin-3-ylmethylideneamino]quinolin-4-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of 6-methoxy-2-methyl-N-[(E)-pyridin-3-ylmethylideneamino]quinolin-4-amine

Chemical Property:

Vapor Pressure:1.2E-09mmHg at 25°C
Boiling Point:487.3°Cat760mmHg
Flash Point:248.5°C
PSA：59.40000
Density:1.19g/cm³
LogP:3.46580
XLogP3:3.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:292.13241115
Heavy Atom Count:22
Complexity:376

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=C2C=C(C=CC2=N1)OC)NN=CC3=CN=CC=C3
Isomeric SMILES:CC1=CC(=C2C=C(C=CC2=N1)OC)N/N=C/C3=CN=CC=C3

Technology Process of 6-methoxy-2-methyl-N-[(E)-pyridin-3-ylmethylideneamino]quinolin-4-amine

There total 5 articles about 6-methoxy-2-methyl-N-[(E)-pyridin-3-ylmethylideneamino]quinolin-4-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 34.0%

: 500-22-1
3-pyridinecarboxaldehyde

: 49612-12-6
1-(6-methoxy-2-methylquinolin-4-yl)hydrazine

: 29125-41-5
6-methoxy-2-methyl-4-(2-(pyridin-3-ylmethylene)hydrazinyl)quinoline

Guidance literature:: In methanol; for 3h;
DOI:10.1016/j.ejmech.2019.111649

Reference yield:

: 5-(1'-((4'-methoxyphenyl)amino)ethylidene)-2,2-dimethyl-1,3-dioxane-4,6-dione

: 29125-41-5
6-methoxy-2-methyl-4-(2-(pyridin-3-ylmethylene)hydrazinyl)quinoline

Guidance literature:: Multi-step reaction with 4 steps

1: diphenylether / 0.5 h / 200 °C / Microwave irradiation

2: trichlorophosphate / 110 °C

3: hydrazine hydrate / ethanol / Reflux

4: methanol / 3 h

With hydrazine hydrate; trichlorophosphate; In methanol; diphenylether; ethanol;
DOI:10.1016/j.ejmech.2019.111649

Reference yield:

: 15644-90-3
6-methoxy-2-methylquinolin-4-ol

: 29125-41-5
6-methoxy-2-methyl-4-(2-(pyridin-3-ylmethylene)hydrazinyl)quinoline

Guidance literature:: Multi-step reaction with 3 steps

1: trichlorophosphate / 110 °C

2: hydrazine hydrate / ethanol / Reflux

3: methanol / 3 h

With hydrazine hydrate; trichlorophosphate; In methanol; ethanol;
DOI:10.1016/j.ejmech.2019.111649