10-Hydroxymethyl-7-methylbenz(c)acridine

Base Information

• Chemical Name: 10-Hydroxymethyl-7-methylbenz(c)acridine
• CAS No.: 160543-08-8
• Molecular Formula: C₁₉H₁₅NO
• Molecular Weight: 273.334
• UNII: HAV3T96WQJ
• DSSTox Substance ID: DTXSID50166928
• Nikkaji Number: J641.052I
• Wikidata: Q83036217
• Mol file: 160543-08-8.mol

Synonyms:160543-08-8;10-Hydroxymethyl-7-methylbenz(c)acridine;10-HYDROXYMETHYL-7-METHYLBENZ[C]ACRIDINE;(7-methylbenzo[c]acridin-10-yl)methanol;CCRIS 7381;HAV3T96WQJ;DTXSID50166928;7-Methylbenz[c]acridine-10-methanol;Benz[c]acridine-10-methanol, 7-methyl-

Chemical Property of 10-Hydroxymethyl-7-methylbenz(c)acridine

Chemical Property:

• Vapor Pressure: 3.31E-12mmHg at 25°C
• Boiling Point: 533.4°Cat760mmHg
• Flash Point: 276.4°C
• PSA: 33.12000
• Density: 1.27g/cm³
• LogP: 4.34190
• XLogP3: 4.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 273.115364102
• Heavy Atom Count: 21
• Complexity: 371

Purity/Quality:

10-HYDROXYMETHYL-7-METHYLBENZ[C]ACRIDINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=C2C=CC(=CC2=NC3=C1C=CC4=CC=CC=C43)CO

Technology Process of 10-Hydroxymethyl-7-methylbenz(c)acridine

There total 2 articles about 10-Hydroxymethyl-7-methylbenz(c)acridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

10-(acetoxymethyl)-7-methylbenz[c]acridine → 10-(hydroxymethyl)-7-methylbenz[c]acridine (160543-08-8)

Guidance literature:

With sodium hydroxide; In ethanol; at 20 ℃; for 0.5h;

DOI:10.1021/tx00044a003

Reference yield:

10-(bromomethyl)-7-methylbenz[c]acridine → 10-(hydroxymethyl)-7-methylbenz[c]acridine (160543-08-8)

Guidance literature:

Multi-step reaction with 2 steps

1: ethanol / 2 h / Heating

2: aq. NaOH / aq. ethanol / 0.5 h / 20 °C

With sodium hydroxide; In ethanol; 1: Acetylation / 2: Deacetylation;

DOI:10.1021/tx00044a003