2-Amino-2-(4-(trifluoromethyl)phenyl)ethanol

Base Information

Chemical Name:2-Amino-2-(4-(trifluoromethyl)phenyl)ethanol
CAS No.:473416-36-3
Molecular Formula:C9H10F3NO
Molecular Weight:205.17700
Hs Code.:
DSSTox Substance ID:DTXSID00564733
Mol file:473416-36-3.mol

Synonyms:2-Amino-2-(4-(trifluoromethyl)phenyl)ethanol;473416-36-3;2-amino-2-[4-(trifluoromethyl)phenyl]ethanol;2-Amino-2-(4-trifluoromethyl-phenyl)-ethanol;2-Amino-2-[4-(trifluoromethyl)phenyl]ethan-1-ol;MFCD11213652;2-amino-2-(4-(trifluoromethyl)phenyl)ethan-1-ol;(2R)-2-Amino-2-(4-trifluoromethyl-phenyl)-ethanol;(2S)-2-Amino-2-(4-trifluoromethyl-phenyl)-ethanol;MFCD09253774;MFCD09253775;(R)-2-Amino-2-(4-trifluoromethylphenyl)ethanol;(R)-2-amino-2-(4-(trifluoromethyl)phenyl)ethan-1-ol;SCHEMBL996527;DTXSID00564733;AKOS005265646;SB36392;SB36492;SB37275;PS-16479;SY320941;SY324920;SY344977;beta-Amino-4-(trifluoromethyl)benzeneethanol;CS-0089928;EN300-149494;N11179

Suppliers and Price of 2-Amino-2-(4-(trifluoromethyl)phenyl)ethanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

J&W Pharmlab
2-Amino-2-(4-trifluoromethyl-phenyl)-ethanol 96%
5g
$ 2390.00

J&W Pharmlab
2-Amino-2-(4-trifluoromethyl-phenyl)-ethanol 96%
1g
$ 598.00

J&W Pharmlab
2-Amino-2-(4-trifluoromethyl-phenyl)-ethanol 96%
100mg
$ 163.00

J&W Pharmlab
2-Amino-2-(4-trifluoromethyl-phenyl)-ethanol 96%
50mg
$ 131.00

J&W Pharmlab
2-Amino-2-(4-trifluoromethyl-phenyl)-ethanol 96%
250mg
$ 225.00

J&W Pharmlab
2-Amino-2-(4-trifluoromethyl-phenyl)-ethanol 96%
500mg
$ 349.00

Crysdot
2-Amino-2-(4-(trifluoromethyl)phenyl)ethanol 95+%
1g
$ 400.00

Chemenu
2-amino-2-(4-(trifluoromethyl)phenyl)ethan-1-ol 95%
1g
$ 310.00

American Custom Chemicals Corporation
2-AMINO-2-(4-(TRIFLUOROMETHYL)PHENYL)ETHANOL 95.00%
5MG
$ 502.17

Alichem
2-Amino-2-(4-(trifluoromethyl)phenyl)ethanol
1g
$ 314.29

Total 14 raw suppliers

Chemical Property of 2-Amino-2-(4-(trifluoromethyl)phenyl)ethanol

Chemical Property:

PSA：46.25000
LogP:2.39780
XLogP3:1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:205.07144843
Heavy Atom Count:14
Complexity:175

Purity/Quality:

99%, ^*data from raw suppliers

2-Amino-2-(4-trifluoromethyl-phenyl)-ethanol 96% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1C(CO)N)C(F)(F)F

Technology Process of 2-Amino-2-(4-(trifluoromethyl)phenyl)ethanol

There total 19 articles about 2-Amino-2-(4-(trifluoromethyl)phenyl)ethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 1312719-16-6
(Rs,1S)-N-(2-(tert-butyldimethylsilyloxy)-1-(4-(trifluoromethyl)phenyl)ethyl)-2-methylpropane-2-sulfinamide

: 287394-20-1,473416-36-3
(S)-(+)-2-amino-2-[p-(trifluoromethyl)phenyl]ethanol

Guidance literature:: (Rs,1S)-N-(2-(tert-butyldimethylsilyloxy)-1-(4-(trifluoromethyl)phenyl)ethyl)-2-methylpropane-2-sulfinamide; With hydrogenchloride; In methanol; at 20 ℃; for 3h;

With sodium hydrogencarbonate; In water;
DOI:10.1016/j.tetasy.2011.01.011

Reference yield: 85.0%

: 144789-75-3
(S)-2-amino-2-(4-(trifluoromethyl)phenyl)acetic acid

: 287394-20-1,473416-36-3
(S)-(+)-2-amino-2-[p-(trifluoromethyl)phenyl]ethanol

Guidance literature:: (S)-2-amino-2-(4-(trifluoromethyl)phenyl)acetic acid; With sodium tetrahydroborate; In tetrahydrofuran; for 0.166667h; Sealed tube; Inert atmosphere; Cooling with ice;

With iodine; In tetrahydrofuran; for 16h; Sealed tube; Inert atmosphere; Reflux;
DOI:10.1021/jacs.9b01091