[(2R,3S,5R)-5-(6-benzamidopurin-9-yl)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]oxolan-3-yl] (4-chlorophenyl) phosphate;triethylazanium

Base Information

Chemical Name:[(2R,3S,5R)-5-(6-benzamidopurin-9-yl)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]oxolan-3-yl] (4-chlorophenyl) phosphate;triethylazanium
CAS No.:82893-26-3
Molecular Formula:C₆H₁₅N*C₄₄H₃₉ClN₅O₉P
Molecular Weight:949.44
Hs Code.:

[(2R,3S,5R)-5-(6-benzamidopurin-9-yl)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]oxolan-3-yl] (4-chlorophenyl) phosphate;triethylazanium

Synonyms:

Suppliers and Price of [(2R,3S,5R)-5-(6-benzamidopurin-9-yl)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]oxolan-3-yl] (4-chlorophenyl) phosphate;triethylazanium

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of [(2R,3S,5R)-5-(6-benzamidopurin-9-yl)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]oxolan-3-yl] (4-chlorophenyl) phosphate;triethylazanium

Chemical Property:

Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:12
Rotatable Bond Count:18
Exact Mass:948.3378420
Heavy Atom Count:67
Complexity:1400

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC[NH+](CC)CC.COC1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)OCC4C(CC(O4)N5C=NC6=C(N=CN=C65)NC(=O)C7=CC=CC=C7)OP(=O)([O-])OC8=CC=C(C=C8)Cl
Isomeric SMILES:CC[NH+](CC)CC.COC1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)OC[C@@H]4[C@H](C[C@@H](O4)N5C=NC6=C(N=CN=C65)NC(=O)C7=CC=CC=C7)OP(=O)([O-])OC8=CC=C(C=C8)Cl

Technology Process of [(2R,3S,5R)-5-(6-benzamidopurin-9-yl)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]oxolan-3-yl] (4-chlorophenyl) phosphate;triethylazanium

There total 5 articles about [(2R,3S,5R)-5-(6-benzamidopurin-9-yl)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]oxolan-3-yl] (4-chlorophenyl) phosphate;triethylazanium which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 57777-86-3
5'-O-(dimethoxytrityl)-N-benzoyladenine 3'-(p-chlorophenylcyanoethyl phosphate)

: 82893-26-3
4-chlorophenyl 5'-O-(4,4'-dimethoxytrityl)-N⁶-benzoyl-2'-deoxyadenosin-3'-yl phosphate triethylammonium salt

Guidance literature:: With water; triethylamine; In pyridine; Ambient temperature;
DOI:10.1021/jo00199a039

Reference yield:

: Phosphorsaeure-(p-chlorphenylester)-dichlorid

: 82893-26-3
4-chlorophenyl 5'-O-(4,4'-dimethoxytrityl)-N⁶-benzoyl-2'-deoxyadenosin-3'-yl phosphate triethylammonium salt

Guidance literature:: Multi-step reaction with 2 steps

1: NEt₃ / acetonitrile / 0.33 h

2: acetonitrile; pyridine / 0.75 h / Ambient temperature

With triethylamine; In pyridine; acetonitrile;

Reference yield:

: 40615-36-9
4,4'-dimethoxytrityl chloride

: 82893-26-3
4-chlorophenyl 5'-O-(4,4'-dimethoxytrityl)-N⁶-benzoyl-2'-deoxyadenosin-3'-yl phosphate triethylammonium salt

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine / 5 h / Ambient temperature

2: acetonitrile; pyridine / 0.75 h / Ambient temperature

In pyridine; acetonitrile;