2-Pyrrolidinecarboxamide,N-cyclopropyl-,(2S)-(9CI)

Base Information

Chemical Name:2-Pyrrolidinecarboxamide,N-cyclopropyl-,(2S)-(9CI)
CAS No.:477575-60-3
Molecular Formula:C8H14N2O
Molecular Weight:154.21000
Hs Code.:
Mol file:477575-60-3.mol

Synonyms:(S)-N-cyclopropylpyrrolidine-2-carboxamide;pyrrolidine-2-carboxylic acid cyclopropylamide;(S)-pyrrolidine-2-carboxylic acid cyclopropylamide;

Suppliers and Price of 2-Pyrrolidinecarboxamide,N-cyclopropyl-,(2S)-(9CI)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
(2S)-N-CYCLOPROPYLPYRROLIDINE-2-CARBOXAMIDE 95.00%
5MG
$ 504.77

Total 1 raw suppliers

Chemical Property of 2-Pyrrolidinecarboxamide,N-cyclopropyl-,(2S)-(9CI)

Chemical Property:

PSA：41.13000
LogP:0.73670

Purity/Quality:: (2S)-N-CYCLOPROPYLPYRROLIDINE-2-CARBOXAMIDE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-Pyrrolidinecarboxamide,N-cyclopropyl-,(2S)-(9CI)

There total 4 articles about 2-Pyrrolidinecarboxamide,N-cyclopropyl-,(2S)-(9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 143978-12-5
(S)-tert-butyl 2-(cyclopropylcarbamoyl)pyrrolidine-1-carboxylate

: 477575-60-3,744992-83-4
(S)-N-cyclopropyl-pyrrolidine-2-carboxamide

Guidance literature:: With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 5h; Inert atmosphere;
DOI:10.1007/s10562-011-0585-3

Reference yield:

: 60143-27-3
(S)-2-cyclopropylcarbamoyl-pyrrolidine-1-carboxylic acid benzyl ester

: 477575-60-3,744992-83-4
(S)-N-cyclopropyl-pyrrolidine-2-carboxamide

Guidance literature:: palladium-carbon;

Reference yield:

: 15761-39-4,59433-50-0
1-(tert-butoxycarbonyl)-L-proline

: 477575-60-3,744992-83-4
(S)-N-cyclopropyl-pyrrolidine-2-carboxamide

Guidance literature:: Multi-step reaction with 2 steps

1.1: Et₃N; iBuOCOCl / CH₂Cl₂ / 0 °C

1.2: CH₂Cl₂ / 0 - 20 °C

2.1: TFA / CH₂Cl₂

2.2: aq. NaOH / CH₂Cl₂ / pH 8 - 10

With triethylamine; trifluoroacetic acid; isobutyl chloroformate; In dichloromethane;
DOI:10.1021/jo062336i