5,6,7,8-Tetrahydroquinazoline-2,4-diamine

Base Information

Chemical Name:5,6,7,8-Tetrahydroquinazoline-2,4-diamine
CAS No.:1899-40-7
Molecular Formula:C8H12N4
Molecular Weight:164.21
Hs Code.:2933990090
European Community (EC) Number:217-594-4
NSC Number:33682
DSSTox Substance ID:DTXSID60172414
Nikkaji Number:J39.653B
Wikidata:Q83042510
ChEMBL ID:CHEMBL269317
Mol file:1899-40-7.mol

Synonyms:5,6,7,8-Tetrahydroquinazoline-2,4-diamine;1899-40-7;5,6,7,8-Tetrahydro-quinazoline-2,4-diamine;2,4-diamino-5,6,7,8-tetrahydroquinazoline;EINECS 217-594-4;AI3-50337;NSC33682;Oprea1_357965;Oprea1_387932;MLS000688355;CHEMBL269317;SCHEMBL3563842;DTXSID60172414;HMS1607H16;HMS2774N09;BAA89940;NSC 33682;NSC-33682;STK019231;AKOS000269628;NCGC00245526-01;SMR000283780;BB 0221232;EU-0067538;2,4-Quinazolinediamine, 5,6,7,8-tetrahydro-;SR-01000395268;SR-01000395268-1;Z56791215;F0777-0393

Suppliers and Price of 5,6,7,8-Tetrahydroquinazoline-2,4-diamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Oakwood
5,6,7,8-Tetrahydroquinazoline-2,4-diamine tech
5g
$ 550.00

Oakwood
5,6,7,8-Tetrahydroquinazoline-2,4-diamine tech
500mg
$ 125.00

Total 8 raw suppliers

Chemical Property of 5,6,7,8-Tetrahydroquinazoline-2,4-diamine

Chemical Property:

Vapor Pressure:4.04E-08mmHg at 25°C
Boiling Point:445.2°C at 760 mmHg
Flash Point:253.4°C
PSA：77.82000
Density:1.29g/cm³
LogP:1.68220
XLogP3:0.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:0
Exact Mass:164.106196400
Heavy Atom Count:12
Complexity:161

Purity/Quality:

99% ^*data from raw suppliers

5,6,7,8-Tetrahydroquinazoline-2,4-diamine tech ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CCC2=C(C1)C(=NC(=N2)N)N

Technology Process of 5,6,7,8-Tetrahydroquinazoline-2,4-diamine

There total 7 articles about 5,6,7,8-Tetrahydroquinazoline-2,4-diamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 36.0%

: 79050-47-8
4-amino-2-methylsulfinyl-5,6,7,8-tetrahydroquinazoline

: 1899-40-7
2,4-diamino-5,6,7,8-tetrahydroquinazoline

Guidance literature:: With ammonia; In ethanol; water; at 180 ℃; for 7h; in a sealed tube;

Reference yield:

: 108-94-1,11119-77-0,9003-41-2,9075-99-4
cyclohexanone

: 1899-40-7
2,4-diamino-5,6,7,8-tetrahydroquinazoline

Guidance literature:: Multi-step reaction with 3 steps

1: 67 percent / pyrrolidine / 7 h / 150 °C / in a sealed tube

2: 60 percent / 70percent m-chloroperbenzoic acid / CHCl₃ / 1 eq. oxid. reagent; 1.) -10 deg C, 1 h; 2.) r.t., overnight

3: 36 percent / NH₃ / H₂O; ethanol / 7 h / 180 °C / in a sealed tube

With ammonia; 3-chloro-benzenecarboperoxoic acid; pyrrolidine; In ethanol; chloroform; water;

Reference yield:

: 77766-03-1
2-methylsulfanyl-5,6,7,8-tetrahydroquinazolin-4-ylamine

: 1899-40-7
2,4-diamino-5,6,7,8-tetrahydroquinazoline

Guidance literature:: Multi-step reaction with 2 steps

1: 60 percent / 70percent m-chloroperbenzoic acid / CHCl₃ / 1 eq. oxid. reagent; 1.) -10 deg C, 1 h; 2.) r.t., overnight

2: 36 percent / NH₃ / H₂O; ethanol / 7 h / 180 °C / in a sealed tube

With ammonia; 3-chloro-benzenecarboperoxoic acid; In ethanol; chloroform; water;