Phenylmethyl N-[(1S)-1-[(chlorosulfonyl)methyl]-2-methylpropyl]carbamate

Base Information

Chemical Name:Phenylmethyl N-[(1S)-1-[(chlorosulfonyl)methyl]-2-methylpropyl]carbamate
CAS No.:477808-39-2
Molecular Formula:C13H18ClNO4S
Molecular Weight:319.809
Hs Code.:
DSSTox Substance ID:DTXSID401149380
Nikkaji Number:J1.755.388G

Synonyms:DTXSID401149380;477808-39-2;Phenylmethyl N-[(1S)-1-[(chlorosulfonyl)methyl]-2-methylpropyl]carbamate

Suppliers and Price of Phenylmethyl N-[(1S)-1-[(chlorosulfonyl)methyl]-2-methylpropyl]carbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Phenylmethyl N-[(1S)-1-[(chlorosulfonyl)methyl]-2-methylpropyl]carbamate

Chemical Property:

XLogP3:3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:7
Exact Mass:319.0645069
Heavy Atom Count:20
Complexity:399

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)C(CS(=O)(=O)Cl)NC(=O)OCC1=CC=CC=C1
Isomeric SMILES:CC(C)[C@@H](CS(=O)(=O)Cl)NC(=O)OCC1=CC=CC=C1

Technology Process of Phenylmethyl N-[(1S)-1-[(chlorosulfonyl)methyl]-2-methylpropyl]carbamate

There total 13 articles about Phenylmethyl N-[(1S)-1-[(chlorosulfonyl)methyl]-2-methylpropyl]carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.0%

: Sodium; (S)-2-benzyloxycarbonylamino-3-methyl-butane-1-sulfonate

: 477808-39-2
(S)-2-benzyloxycarbonylamino-3-methylbutane-1-sulfonyl chloride

Guidance literature:: With phosgene; at 20 ℃;
DOI:10.1016/j.tetlet.2009.02.130

Reference yield:

: (S)-2-Benzyloxycarbonylamino-3-methyl-butane-1-sulfonic acid

: 477808-39-2
(S)-2-benzyloxycarbonylamino-3-methylbutane-1-sulfonyl chloride

Guidance literature:: (S)-2-Benzyloxycarbonylamino-3-methyl-butane-1-sulfonic acid; With sodium acetate; In ethanol; at 20 ℃; for 1h;

With N,N-dimethyl-formamide; In dichloromethane; toluene; at 20 ℃; for 2h;
DOI:10.1055/s-2003-41029

Reference yield:

: 137719-71-2
(S)-2-<(benzyloxycarbonyl)amino>-3-methylbutyl ethanethioate

: 477808-39-2
(S)-2-benzyloxycarbonylamino-3-methylbutane-1-sulfonyl chloride

Guidance literature:: Multi-step reaction with 2 steps

1.1: water; dihydrogen peroxide; acetic acid / 20 °C

2.1: 10% palladium on activated charcoal; sodium acetate / water / 20 °C

2.2: 20 °C

With 10% palladium on activated charcoal; water; dihydrogen peroxide; sodium acetate; acetic acid; In water;
DOI:10.1016/j.bmc.2011.02.014