NULL

Base Information

• Chemical Name: NULL
• CAS No.: 479423-44-4
• Molecular Formula: C16H17NO2
• Molecular Weight: 255.316
• Mol file: 479423-44-4.mol

Synonyms:N-tert-butoxycarbonyl-1-naphthylaldimine;N-(tert-butoxycarbonyl)-1-naphthaldimine;(E)-tert-Butyl (naphthalen-1-ylmethylene)carbamate;1-naphthaldehyde N-(tert-butoxycarbonyl)imine;naphthalen-1-ylmethylene-carbamic acid tert-butyl ester;tert-butyl (naphthalen-1-ylmethylene)carbamate;

Chemical Property of NULL

Chemical Property:

• PSA: 38.66000
• LogP: 4.19380
• Storage Temp.: 2-8°C

Purity/Quality:

98%,99%, ^*data from raw suppliers

tert-Butyl(naphthalen-1-ylmethylene)carbamate 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of NULL

There total 5 articles about NULL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

tert-butyl naphthalen-1-yl(phenylsulfonyl)methylcarbamate (479423-31-9) → tert-butyl naphthalen-1-ylmethylenecarbamate (479423-44-4)

Guidance literature:

With potassium carbonate; sodium sulfate; In tetrahydrofuran; at 20 ℃; for 16h; Molecular sieve; Reflux;

DOI:10.1002/anie.200903063

Reference yield:

tert-butyl carbazate (4248-19-5) → tert-butyl naphthalen-1-ylmethylenecarbamate (479423-44-4)

Guidance literature:

Multi-step reaction with 2 steps

1: formic acid / methanol; H₂O / 72 h / 20 °C

2: anhydrous potassium carbonate / tetrahydrofuran / 17 h / Heating

With formic acid; potassium carbonate; In tetrahydrofuran; methanol; water;

DOI:10.1002/anie.200502674

Reference yield:

1-naphthaldehyde (66-77-3) → tert-butyl naphthalen-1-ylmethylenecarbamate (479423-44-4)

Guidance literature:

Multi-step reaction with 2 steps

1: formic acid / methanol; H₂O / 72 h / 20 °C

2: anhydrous potassium carbonate / tetrahydrofuran / 17 h / Heating

With formic acid; potassium carbonate; In tetrahydrofuran; methanol; water;

DOI:10.1002/anie.200502674

upstream raw materials:

tert-butyl naphthalen-1-yl(phenylsulfonyl)methylcarbamate

tert-butyl carbazate

1-naphthaldehyde

1-naphthaldimine

Refernces

• 1、 Choi, Bonnie,Saxena, Aakarsh,Smith, Joshua J.,Churchill, Gwydion H.,Lam, Hon Wai. "Enantioselective copper-catalyzed reductive coupling of vinylazaarenes with n -boc aldimines". supporting information. p. 350 - 354. Retrieved 2015/02/19.
• 2、 Wang, Ding,Cao, Peng,Wang, Bing,Jia, Tao,Lou, Yazhou,Wang, Min,Liao, Jian. "Copper(I)-Catalyzed Asymmetric Pinacolboryl Addition of N-Boc-imines Using a Chiral Sulfoxide - Phosphine Ligand". supporting information. p. 2420 - 2423. Retrieved 2015/05/27.