(R)-5-(Hydroxymethyl)-3-(4-hydroxyphenyl)oxazolidin-2-one

Base Information

Chemical Name:(R)-5-(Hydroxymethyl)-3-(4-hydroxyphenyl)oxazolidin-2-one
CAS No.:73422-72-7
Molecular Formula:C10H11 N O4
Molecular Weight:209.202
Hs Code.:
European Community (EC) Number:277-467-4
UNII:8PS8FF5FX8
DSSTox Substance ID:DTXSID90994146
Nikkaji Number:J295.221A
Wikidata:Q82984981
Mol file:73422-72-7.mol

Synonyms:73422-72-7;8PS8FF5FX8;(R)-5-(Hydroxymethyl)-3-(4-hydroxyphenyl)oxazolidin-2-one;EINECS 277-467-4;UNII-8PS8FF5FX8;5-(Hydroxymethyl)-3-(4-hydroxyphenyl)-2-oxazolidinone, (R)-;SCHEMBL9549439;DTXSID90994146;WVULNOZIAYBGLE-SECBINFHSA-N;(5R)-5-(HYDROXYMETHYL)-3-(4-HYDROXYPHENYL)-1,3-OXAZOLIDIN-2-ONE;NS00060249;5-(hydroxymethyl)-3-(4-hydroxyphenyl)-1,3-oxazolidin-2-one;2-Oxazolidinone, 5-(hydroxymethyl)-3-(4-hydroxyphenyl)-, (R)-

Suppliers and Price of (R)-5-(Hydroxymethyl)-3-(4-hydroxyphenyl)oxazolidin-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of (R)-5-(Hydroxymethyl)-3-(4-hydroxyphenyl)oxazolidin-2-one

Chemical Property:

Vapor Pressure:9.98E-08mmHg at 25°C
Boiling Point:417.8°C at 760 mmHg
Flash Point:206.5°C
PSA：70.00000
Density:1.408g/cm³
LogP:0.77470
XLogP3:0.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:209.06880783
Heavy Atom Count:15
Complexity:238

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(OC(=O)N1C2=CC=C(C=C2)O)CO
Isomeric SMILES:C1[C@@H](OC(=O)N1C2=CC=C(C=C2)O)CO

Technology Process of (R)-5-(Hydroxymethyl)-3-(4-hydroxyphenyl)oxazolidin-2-one

There total 3 articles about (R)-5-(Hydroxymethyl)-3-(4-hydroxyphenyl)oxazolidin-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 130641-82-6
(R)-3-<4-(benzyloxy)phenyl>-5-(hydroxymethyl)-2-oxazolidinone

: 73422-72-7
(R)-5-(hydroxymethyl)-3-(4-hydroxyphenyl)-2-oxazolidinone

Guidance literature:: With hydrogen; palladium on activated charcoal; In methanol; ethyl acetate; for 5h; under 760 Torr;

Reference yield:

: 6373-46-2
p-benzyloxyaniline

: 73422-72-7
(R)-5-(hydroxymethyl)-3-(4-hydroxyphenyl)-2-oxazolidinone

Guidance literature:: Multi-step reaction with 3 steps

1: 42 percent / ethanol / 1.) 55 deg C, 20 h, 2.) reflux, 3 h

2: 66 percent / sodium methoxide / toluene / 100 °C

3: H₂ / 10percent Pd/C / methanol; ethyl acetate / 5 h / 760 Torr

With hydrogen; sodium methylate; palladium on activated charcoal; In methanol; ethanol; ethyl acetate; toluene;

Reference yield:

: 130641-80-4
(R)-3-<<4-(benzyloxy)phenyl>amino>-1,2-propanediol

: 73422-72-7
(R)-5-(hydroxymethyl)-3-(4-hydroxyphenyl)-2-oxazolidinone

Guidance literature:: Multi-step reaction with 2 steps

1: 66 percent / sodium methoxide / toluene / 100 °C

2: H₂ / 10percent Pd/C / methanol; ethyl acetate / 5 h / 760 Torr

With hydrogen; sodium methylate; palladium on activated charcoal; In methanol; ethyl acetate; toluene;