(4-Hydroxyphenyl)phenylarsinic acid

Base Information

• Chemical Name: (4-Hydroxyphenyl)phenylarsinic acid
• CAS No.: 7150-95-0
• Molecular Formula: C₁₂H₁₁AsO₃
• Molecular Weight: 278.139
• NSC Number: 41376
• DSSTox Substance ID: DTXSID90285324
• Wikidata: Q82020656
• ChEMBL ID: CHEMBL1446804
• Mol file: 7150-95-0.mol

Synonyms:MLS000737038;7150-95-0;(4-hydroxyphenyl)phenylarsinic acid;NSC41376;ANTINEOPLASTIC-41376;SCHEMBL9167331;CHEMBL1446804;DTXSID90285324;HMS2762O04;NSC-41376;SMR000393994

Chemical Property of (4-Hydroxyphenyl)phenylarsinic acid

Chemical Property:

• Vapor Pressure: 6.87E-11mmHg at 25°C
• Boiling Point: 501.8°C at 760 mmHg
• Flash Point: 271.4°C
• PSA: 57.53000
• LogP: 0.37140
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 277.992414
• Heavy Atom Count: 16
• Complexity: 265

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)[As](=O)(C2=CC=C(C=C2)O)O

Technology Process of (4-Hydroxyphenyl)phenylarsinic acid

There total 3 articles about (4-Hydroxyphenyl)phenylarsinic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(4-amino-phenyl)-phenyl-arsinic acid (779354-73-3) → NSC 41376 (7150-95-0)

Guidance literature:

With sulfuric acid; sodium nitrite; anschliessend Erwaermen;

DOI:10.1021/ja01282a030 DOI:10.1021/ja01318a044

Reference yield:

(4-nitro-phenyl)-phenyl-arsinic acid (18789-52-1) → NSC 41376 (7150-95-0)

Guidance literature:

Multi-step reaction with 2 steps

1: aqueous iron (II)-sulfate; aq. NaOH solution

2: aqueous sulfuric acid; sodium nitrite / anschliessend Erwaermen

With sodium hydroxide; sulfuric acid; iron(II) sulfate; sodium nitrite;

DOI:10.1021/ja01318a044

Reference yield:

4-nitro-aniline (100-01-6,104810-17-5) → NSC 41376 (7150-95-0)

Guidance literature:

Multi-step reaction with 3 steps

1: water / Hydrogenation_.anschliessend mit Arsenosobenzol und wss. Natronlauge

2: aqueous iron (II)-sulfate; aq. NaOH solution

3: aqueous sulfuric acid; sodium nitrite / anschliessend Erwaermen

With sodium hydroxide; sulfuric acid; water; iron(II) sulfate; sodium nitrite;

DOI:10.1021/ja01318a044

upstream raw materials:

(4-amino-phenyl)-phenyl-arsinic acid

(4-nitro-phenyl)-phenyl-arsinic acid

4-nitro-aniline

Downstream raw materials:

(4-hydroxy-3-nitro-phenyl)-(3-nitro-phenyl)-arsinic acid

2-[(4-hydroxy-phenyl)-phenyl-arsinomercapto]-benzoic acid