2-[Piperazin-1-yl-[4-(trifluoromethyl)phenyl]methyl]quinoline

Base Information

Chemical Name:2-[Piperazin-1-yl-[4-(trifluoromethyl)phenyl]methyl]quinoline
CAS No.:5008-25-3
Molecular Formula:C₁₆H₂₁IO₅
Molecular Weight:420.244
Hs Code.:
DSSTox Substance ID:DTXSID80409557
Mol file:5008-25-3.mol

Synonyms:5008-25-3;2-[piperazin-1-yl-[4-(trifluoromethyl)phenyl]methyl]quinoline;DTXSID80409557

Suppliers and Price of 2-[Piperazin-1-yl-[4-(trifluoromethyl)phenyl]methyl]quinoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 2-[Piperazin-1-yl-[4-(trifluoromethyl)phenyl]methyl]quinoline

Chemical Property:

Vapor Pressure:1.53E-08mmHg at 25°C
Boiling Point:457.1°C at 760 mmHg
Flash Point:230.3°C
Density:1.252g/cm³
XLogP3:4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:3
Exact Mass:371.16093214
Heavy Atom Count:27
Complexity:470

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CCN1)C(C2=CC=C(C=C2)C(F)(F)F)C3=NC4=CC=CC=C4C=C3

Technology Process of 2-[Piperazin-1-yl-[4-(trifluoromethyl)phenyl]methyl]quinoline

There total 3 articles about 2-[Piperazin-1-yl-[4-(trifluoromethyl)phenyl]methyl]quinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 51839-16-8
5-iodoisophthalic acid

: 5008-25-3
3-Jod-5-propoxycarbonyl-benzoesaeure-<3-methoxy-butylester>

Guidance literature:: Multi-step reaction with 3 steps

1: HCl

2: aq. NaOH / dimethylformamide

3: dimethylformamide

With hydrogenchloride; sodium hydroxide; In N,N-dimethyl-formamide;
DOI:10.1021/jm00319a050

Reference yield:

: 4862-97-9
5-Jod-isophthalsaeure-di-n-propylester

: 5008-25-3
3-Jod-5-propoxycarbonyl-benzoesaeure-<3-methoxy-butylester>

Guidance literature:: Multi-step reaction with 2 steps

1: aq. NaOH / dimethylformamide

2: dimethylformamide

With sodium hydroxide; In N,N-dimethyl-formamide;
DOI:10.1021/jm00319a050