Benzenamine, 2,4,6-trimethyl-N-(1-phenylpropylidene)-

Base Information

• Chemical Name: Benzenamine, 2,4,6-trimethyl-N-(1-phenylpropylidene)-
• CAS No.: 487061-08-5
• Molecular Formula: C18H21N
• Molecular Weight: 251.371
• Mol file: 487061-08-5.mol

Synonyms:

Chemical Property of Benzenamine, 2,4,6-trimethyl-N-(1-phenylpropylidene)-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Benzenamine, 2,4,6-trimethyl-N-(1-phenylpropylidene)-

There total 1 articles about Benzenamine, 2,4,6-trimethyl-N-(1-phenylpropylidene)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.0%

1-Phenylprop-1-yne (673-32-5) + 2,4,6-trimethylaniline (88-05-1) → (mesityl)N=CPhCH2Me (487061-08-5) + C18H21N

Guidance literature:

With C₃₃H₄₉Cl₂N₂PPd; silver trifluoromethanesulfonate; In acetonitrile; at 80 ℃; for 25h; Inert atmosphere; Schlenk technique;

DOI:10.1002/ejic.201701342

Reference yield: 80.4%

nickel(II) bromide dimethoxyethane (28923-39-9) + (mesityl)N=CPhCH2Me (487061-08-5) + chloro-diphenylphosphine (1079-66-9,74391-44-9) → [((mesityl)N=CPhCHMePPh2)NiBr2] (487061-49-4)

Guidance literature:

With LiN(i-Pr)2; In diethyl ether; dichloromethane; (Ar); standard Schlenk technique; soln. of Li compd. in Et2O was added to soln. of imine in Et2O at -78°C; soln. stirred for 20 min; warmed to room temp. and stirred for 1 h; Ph2PCl added at -78°C; soln. stirred for 15 min at -78°C; warmed to room temp. and stirred for 1 h; filtered through silica gel inEt2O followed by THF; evapd.; Ni complex and CH2Cl2 were added to imine phosphine ligand; soln. was stirred at room temp. for 2 h; evapd.; residue washed (Et2O; hexane); elem. anal.;

DOI:10.1021/om0206305

upstream raw materials:

1-Phenylprop-1-yne

2,4,6-trimethylaniline

Downstream raw materials:

[((mesityl)N=CPhCHMePPh₂)NiBr₂]