2-Iodocinnamic acid

Base Information

Chemical Name:2-Iodocinnamic acid
CAS No.:1643-34-1
Molecular Formula:C9H7 I O2
Molecular Weight:274.06
Hs Code.:2916399090
European Community (EC) Number:807-199-0
Nikkaji Number:J3.055.003J
Mol file:1643-34-1.mol

Synonyms:2-Iodocinnamic acid;(2E)-3-(2-iodophenyl)prop-2-enoic acid;1643-34-1;90276-19-0;(E)-3-(2-iodophenyl)prop-2-enoic acid;3-(2-Iodophenyl)acrylic acid;2-Propenoic acid, 3-(2-iodophenyl)-, (E)-;2-Iodo-cinnamic acid;2-Iodobenzeneacrylic acid;SCHEMBL557026;SBCFNNJYIXFMFS-AATRIKPKSA-N;AKOS024255688;2-Propenoic acid, 3-(2-iodophenyl)-(E)-;(2E)-3-(2-Iodophenyl)-2-propenoic acid #

Suppliers and Price of 2-Iodocinnamic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Labseeker
2-iodocinnamicacid 95
10g
$ 2163.00

American Custom Chemicals Corporation
2-IODOCINNAMIC ACID 95.00%
5MG
$ 504.05

Total 6 raw suppliers

Chemical Property of 2-Iodocinnamic acid

Chemical Property:

Vapor Pressure:8.05E-06mmHg at 25°C
Boiling Point:360.3°C at 760 mmHg
Flash Point:171.7°C
PSA：37.30000
Density:1.862g/cm³
LogP:2.38900
XLogP3:2.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:273.94908
Heavy Atom Count:12
Complexity:189

Purity/Quality:

99% ^*data from raw suppliers

2-iodocinnamicacid 95 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C(=C1)C=CC(=O)O)I
Isomeric SMILES:C1=CC=C(C(=C1)/C=C/C(=O)O)I

Technology Process of 2-Iodocinnamic acid

There total 4 articles about 2-Iodocinnamic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 7345-79-1,20595-39-5,7499-56-1
2-bromocinnamic acid

: 1643-34-1
3-(2-iodophenyl)acrylic acid

Guidance literature:: With tributylphosphine; sodium iodide; nickel dibromide; In 1-methyl-pyrrolidin-2-one; at 140 ℃; for 16h; Inert atmosphere; Molecular sieve; Sealed tube;
DOI:10.1039/c2cc30956d

Reference yield:

: 378759-67-2
ethyl (E)-3-(2-iodophenyl)-2-propenoate

: 1643-34-1
3-(2-iodophenyl)acrylic acid

Guidance literature:: With lithium hydroxide; In ethanol; at 0 - 22 ℃; for 16h; Inert atmosphere;
DOI:10.1002/chem.201704277

Reference yield:

: 26260-02-6
2-iodobenzaldehyde

: 1643-34-1
3-(2-iodophenyl)acrylic acid

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium hydride / dichloromethane; mineral oil / 0.08 h / 0 °C / Inert atmosphere

1.2: 2 h / 0 °C / Inert atmosphere

2.1: lithium hydroxide / ethanol / 16 h / 0 - 22 °C / Inert atmosphere

With sodium hydride; lithium hydroxide; In ethanol; dichloromethane; mineral oil;
DOI:10.1002/chem.201704277