Technology Process of Hexanoic acid,
4-(1-methylethyl)-6-(phenylsulfonyl)-5-[(phenylsulfonyl)methyl]-, methyl
ester
There total 10 articles about Hexanoic acid,
4-(1-methylethyl)-6-(phenylsulfonyl)-5-[(phenylsulfonyl)methyl]-, methyl
ester which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 7 steps
1.1: 6.0 g / lithium chloride; 1,8-diazabicyclo[5.4.0]undec-7-ene / acetonitrile / -10 - 20 °C
2.1: diisobutylaluminum hydride / toluene; tetrahydrofuran / 2 h
3.1: 1.77 g / N,N'-diisopropylethylamine / CH2Cl2 / 0.5 h / 20 °C
4.1: n-butyllithium / hexane; tetrahydrofuran / 0.25 h / -78 °C
4.2: 68 percent / tetrahydrofuran; hexane / 2 h / 20 °C
5.1: 96 percent / tetra-butylammoniumfluoride; acetic acid / tetrahydrofuran / 19 h / 20 °C
6.1: ruthenium trichloride hydrate; sodium metaperiodate / acetonitrile; CCl4 / 5 h / 20 °C
7.1: 575 mg / ethyl acetate / 20 °C
With
ruthenium trichloride; sodium periodate; n-butyllithium; tetrabutyl ammonium fluoride; diisobutylaluminium hydride; acetic acid; 1,8-diazabicyclo[5.4.0]undec-7-ene; N-ethyl-N,N-diisopropylamine; lithium chloride;
In
tetrahydrofuran; tetrachloromethane; hexane; dichloromethane; ethyl acetate; toluene; acetonitrile;
1.1: Wittig reaction / 4.1: Michael addition;
DOI:10.1021/ol0271436
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: n-butyllithium / hexane; tetrahydrofuran / 0.25 h / -78 °C
1.2: 68 percent / tetrahydrofuran; hexane / 2 h / 20 °C
2.1: 96 percent / tetra-butylammoniumfluoride; acetic acid / tetrahydrofuran / 19 h / 20 °C
3.1: ruthenium trichloride hydrate; sodium metaperiodate / acetonitrile; CCl4 / 5 h / 20 °C
4.1: 575 mg / ethyl acetate / 20 °C
With
ruthenium trichloride; sodium periodate; n-butyllithium; tetrabutyl ammonium fluoride; acetic acid;
In
tetrahydrofuran; tetrachloromethane; hexane; ethyl acetate; acetonitrile;
1.1: Michael addition;
DOI:10.1021/ol0271436
- Guidance literature:
-
Multi-step reaction with 7 steps
1.1: 6.0 g / lithium chloride; 1,8-diazabicyclo[5.4.0]undec-7-ene / acetonitrile / -10 - 20 °C
2.1: diisobutylaluminum hydride / toluene; tetrahydrofuran / 2 h
3.1: 1.77 g / N,N'-diisopropylethylamine / CH2Cl2 / 0.5 h / 20 °C
4.1: n-butyllithium / hexane; tetrahydrofuran / 0.25 h / -78 °C
4.2: 68 percent / tetrahydrofuran; hexane / 2 h / 20 °C
5.1: 96 percent / tetra-butylammoniumfluoride; acetic acid / tetrahydrofuran / 19 h / 20 °C
6.1: ruthenium trichloride hydrate; sodium metaperiodate / acetonitrile; CCl4 / 5 h / 20 °C
7.1: 575 mg / ethyl acetate / 20 °C
With
ruthenium trichloride; sodium periodate; n-butyllithium; tetrabutyl ammonium fluoride; diisobutylaluminium hydride; acetic acid; 1,8-diazabicyclo[5.4.0]undec-7-ene; N-ethyl-N,N-diisopropylamine; lithium chloride;
In
tetrahydrofuran; tetrachloromethane; hexane; dichloromethane; ethyl acetate; toluene; acetonitrile;
1.1: Wittig reaction / 4.1: Michael addition;
DOI:10.1021/ol0271436
